New York City’s high-end real estate market was in a discernible slump long before the coronavirus pandemic came along and all but shuttered the property market across the country. However, there were any number of notable, big dollar deals in the works long before people were asked to shelter in place and non-essential businesses were […]
Investors' farsightedness is needed to reap rewards from the shift in human consumption-spending pattern.
(Bloomberg) -- An experimental program led by Google parent Alphabet Inc. to wipe out disease-causing mosquitoes succeeded in nearly eliminating them from three test sites in California’s Central Valley.Stamping out illness caused by mosquitoes is one of Alphabet unit Verily’s most ambitious public-health projects. The effort appears to be paying off, according to a paper published in the journal Nature Biotechnology on Monday. Verily is also running coronavirus triage and testing in parts of California. Bradley White, the lead scientist on the Debug initiative, said mosquito-suppression is even more important during the pandemic, so that outbreaks of mosquito-borne diseases such as dengue fever don’t further overwhelm hospitals.Since 2017, the company has released millions of lab-bred Aedes aegypti male mosquitoes into several Fresno County neighborhoods during mosquito season. The insects are bred in Verily labs to be infected with a common bacterium called Wolbachia. When these male mosquitoes mate with females in the wild, the offspring never hatch.In results of the trial published on Monday, Verily revealed that throughout the peak of the 2018 mosquito season, from July to October, Wolbachia-infected males successfully suppressed more than 93% of the female mosquito population at field test sites. Only female mosquitoes bite.Working with the local mosquito abatement district and MosquitoMate, which developed the mosquitoes originally, Verily released as many as 80,000 mosquitoes each day in three neighborhoods from April 2018 through October 2018. In most collections, per night Verily found one or zero female mosquitoes in each trap designed to monitor the population. At other sites without the lab-bred bugs, there were as many as 16 females per trap.“We had a vision of what this should look like and we managed to do that pretty perfectly,” said Jacob Crawford, a senior scientist on the Debug project.In the arid climate of the Central Valley, disease is an unlikely result of a mosquito bite. But in the hot, humid regions of the tropics and subtropics, diseases caused by the Aedes aegypti, such as dengue fever, Zika virus and chikungunya, kill tens of thousands of people every year. Releasing masses of Wolbachia-infected mosquitoes into the wild might wipe out entire populations of deadly mosquitoes and the diseases they carry.Verily is not the only organization pursuing an end to mosquito-borne disease. Microsoft Corp. co-Founder Bill Gates has pledged more than $1 billion to help wipe out malaria, including controversial efforts to genetically modify mosquitoes. Infecting mosquitoes with Wolbachia, which occurs naturally in some mosquito species, is a popular approach rooted in an old insect control strategy called sterile insect technique. What Verily’s efforts offer is not just evidence that Wolbachia can help wipe out disease-causing mosquitoes but potential ways to make such efforts work on a massive scale. Last year, Verily released about 14.4 million mosquitoes in Fresno County.Initial small-scale Fresno trials in 2016, run by an upstart called MosquitoMate, were the first time male Aedes aegypti mosquitoes infected with the bacteria were ever released in the U.S. The following year, Verily stepped in, bringing more advanced technology to the breeding and release process that could make it possible to expand such efforts to entire cities or regions.The new paper details many of those technologies, such as an automated process for separating male and female mosquitoes in the lab, and software that helps to determine exactly where to release altered male mosquitoes for maximum effectiveness.“Once you try to start rearing hundreds of thousands of mosquitoes a week, you run into all sorts of problems,” said White. “Mosquitoes may be everywhere, but they are really finicky and difficult to grow.”Verily has expanded its partnerships to include Singapore’s National Environment Agency. Trials there have entered a fourth phase to cover 121 urban residential blocks and about 45,000 residents. Verily is eyeing partnerships in South America and is in talks to launch in the Caribbean.Within a few years, said Crawford, Verily hopes the program will cover entire regions. Without intervention, he said, the public health toll of mosquito-born illness will only grow.“This is something that’s not going away on its own,” he said.For more articles like this, please visit us at bloomberg.comSubscribe now to stay ahead with the most trusted business news source.©2020 Bloomberg L.P.
- WorldNational Review
If the COVID-19 pandemic tails off in a few weeks, months before the alarmists claim it will, they will probably pivot immediately and pat themselves on the back for the brilliant social-distancing controls that they imposed on the world. They will claim that their heroic recommendations averted total calamity. Unfortunately, they will be wrong; and Sweden, which has done almost no mandated social distancing, will probably prove them wrong.Lots of people are rushing to discredit Sweden’s approach, which relies more on calibrated precautions and isolating only the most vulnerable than on imposing a full lockdown. While gatherings of more than 50 people are prohibited and high schools and colleges are closed, Sweden has kept its borders open as well as its preschools, grade schools, bars, restaurants, parks, and shops.President Trump has no use for Sweden’s nuanced approach. Last Wednesday, he smeared it in a spectacular fashion by saying he’d heard that Sweden “gave it a shot, and they saw things that were really frightening, and they went immediately to shutting down the country.” He and the public-health experts who told him this were wrong on both counts and would do better to question their approach. Johan Giesecke, Sweden’s former chief epidemiologist and now adviser to the Swedish Health Agency, says that other nations “have taken political, unconsidered actions” that are not justified by the facts.In the rush to lock down nations and, as a result, crater their economies, no one has addressed this simple yet critical question: How do we know social-isolation controls actually work? And even if they do work for some infectious epidemics, do they work for COVID-19? And even if they work for this novel coronavirus, do they have to be implemented by a certain point in the epidemic? Or are they locking down the barn door after the horses are long gone?In theory, less physical interaction might slow the rate of new infections. But without a good understanding of how long COVID-19 viral particles survive in air, in water, and on contact surfaces, even that is speculative. Without reliable information on what proportion of the population has already been exposed and successfully fought off the coronavirus, it’s worth questioning the value of social-isolation controls. It is possible that the fastest and safest way to “flatten the curve” is to allow young people to mix normally while requiring only the frail and sick to remain isolated.This is, in fact, the first time we have quarantined healthy people rather than quarantining the sick and vulnerable. As Fredrik Erixon, the director of the European Centre for International Political Economy in Brussels, wrote in The Spectator (U.K.) last week: “The theory of lockdown, after all, is pretty niche, deeply illiberal — and, until now, untested. It’s not Sweden that’s conducting a mass experiment. It’s everyone else.”We’ve posed these simple questions to many highly trained infectious-disease doctors, epidemiologists, mathematical disease-modelers, and other smart, educated professionals. It turns out that, while you need proof beyond a reasonable doubt to convict a person of theft and throw them in jail, you don’t need any actual evidence (much less proof) to put millions of people into a highly invasive and burdensome lockdown with no end in sight and nothing to prevent the lockdown from being reimposed at the whim of public-health officials. Is this rational?When we asked what evidence is available to support the utility of quarantine and social isolation, academics point to the Diamond Princess cruise ship, with 700 COVID-19 passenger cases and eight deaths. But the ship is an artificially engineered, densely packed container of humans that bears little resemblance to living conditions in most countries.The other major evidence academics often cite is the course run by the 1918 swine flu, which swept the globe 102 years ago and was not a coronavirus. Philadelphia did not practice social distancing during the 1918 pandemic, but St. Louis did and had a death rate lower than Philadelphia’s. But how is that relevant to today’s crisis? Apart from the post hoc, ergo propter hoc nature of the argument, a key difference was that the GIs returning from World War I Europe who were carrying the swine-flu virus couldn’t fly nonstop from Paris to St. Louis. They had to land at East Coast ports such as Philadelphia. It’s therefore not surprising that the sick GIs rested and convalesced while spreading the virus on the East Coast, and they got better before continuing to St. Louis and other interior cities.Basing the entire architecture of social distancing on the evidence from the 1918 swine flu makes no sense, especially when that architecture causes significant destruction in the lives and livelihoods of most of the American population.But the social-isolation advocates frantically grasp at straws to support shutting down the world. It bothers them that there is one country in the world that hasn’t shut down and that hasn’t socially isolated its population. It bothers them because when this coronavirus epidemic is over, they would probably love to conclude that social isolation worked.Sweden has courageously decided not to endorse a harsh quarantine, and consequently it hasn’t forced its residents into lockdown. “The strategy in Sweden is to focus on social distancing among the known risk groups, like the elderly. We try to use evidence-based measurements,” Emma Frans, a doctor in epidemiology at Sweden’s Karolinska Institute, told Euronews. “We try to adjust everyday life. The Swedish plan is to implement measurements that you can practice for a long time.”The problem with lockdowns is that “you tire the system out,” Anders Tegnell, Sweden’s chief epidemiologist, told the Guardian. “You can’t keep a lockdown going for months -- it’s impossible.” He told Britain’s Daily Mail: “We can’t kill all our services. And unemployed people are a great threat to public health. It’s a factor you need to think about.”If social isolation worked, wouldn’t Sweden, a Nordic country of 10.1 million people, be seeing the number of COVID-19 cases skyrocket into the tens of thousands, blowing past the numbers in Italy or New York City? As of today, there are 401 reported COVID-19 deaths in Sweden.The really good news is that in Sweden’s ICU census, which is updated every 30 minutes nationwide, admissions to every ICU in the country are flat or declining, and they have been for a week. As of this writing (based on currently available data), most of Sweden’s ICU cases today are elderly, and 77 percent have underlying conditions such as heart disease, respiratory disease, kidney disease, and diabetes. Moreover, there hasn’t been a single pediatric ICU case or death in Sweden — so much for the benefits of shutting down schools everywhere else. There are only 25 COVID-19 ICU admissions among all Swedes under the age of 30.Sweden is developing herd immunity by refusing to panic. By not requiring social isolation, Sweden’s young people spread the virus, mostly asymptomatically, as is supposed to happen in a normal flu season. They will generate protective antibodies that make it harder and harder for the Wuhan virus to reach and infect the frail and elderly who have serious underlying conditions. For perspective, the current COVID-19 death rate in Sweden (40 deaths per million of population) is substantially lower than the Swedish death rate in a normal flu season (in 2018, for instance, about 80 per million of population).Compare that with the situation to Switzerland, a similar small European country, which has 8.5 million people. Switzerland is practicing strict social isolation. Yet Switzerland reports 715 cumulative Wuhan-virus deaths as of today, for a death rate nearly double the number in Sweden. What about Norway, another Nordic country that shares a 1,000-mile open border with Sweden, with a language and culture very similar to Sweden’s? Norway (population 5.4 million) has fewer reported COVID-19 deaths (71) than Sweden but a substantially higher rate of coronavirus ICU admissions.On Friday, one of us spoke with Ulf Persson in his office at the Swedish Institute for Health Economics. He said that everyone he knows is calm and steady, behaving with more caution than normal, following such government-mandated social controls as a 50-person limit on gatherings and only sit-down service at bars and restaurants. Persson estimates that the Swedish economy will drop about 4 percent because of the global economic shutdowns. But that’s nothing compared with the Great Depression unemployment levels of 32 percent that the U.S. Federal Reserve Board of St. Louis recently forecast for the United States.Nature’s got this one, folks. We’ve been coping with new viruses for untold generations. The best way is to allow the young and healthy -- those for whom the virus is rarely fatal -- to develop antibodies and herd immunity to protect the frail and sick. As time passes, it will become clearer that social-isolation measures like those in Switzerland and Norway accomplish very little in terms of reducing fatalities or disease, though they crater local and national economies -- increasing misery, pain, death, and disease from other causes as people’s lives are upended and futures are destroyed.John Fund is a columnist for National Review and has reported frequently from Sweden. Joel Hay is a professor in the department of Pharmaceutical Economics and Policy at the University of Southern California. The author of more than 600 peer-reviewed scientific articles and reports, he has collaborated with the Swedish Institute for Health Economics for nearly 40 years.
- EntertainmentCountry Living
Turn off the lights and turn on one of these horror movies for the family.From Country Living
- WorldAssociated Press
They whiled away the week on a sex- and drug-fueled romp: dancing on white-sand beaches and frolicking on a Caribbean island with prostitutes from Europe, some snapping selfies with famous reggaeton artists. For some of Venezuela’s high-flying “Bolichicos" — the privileged offspring of the socialist revolution — the party hasn’t stopped amid a widening pandemic in a country already gripped by crisis. To date, the virus has claimed only seven confirmed fatalities in Venezuela.
Richard Petty Motorsports driver Bubba Wallace must be having a really bad day at Sunday's video game simulation of eNASCAR iRacing Pro Invitational Series last April 5-- enough to rage-quit in the middle of the race and lose a lucrative sponsorship deal.In case you didn't know, the term "rage quit" is a well-known gamer term for a player who gets so mad that they prematurely quit the race.Wallace, who was one of the 32 drivers vying for first place in the Food City Showdown at a Virtual Bristol Motor Speedway, had a messy encounter with one of the racers.During the 11th lap of the 150-lap race, he was pinned into the wall by Clint Bowyer, and also swung up into Wallace's Chevy Camaro—wrecking it in the process. Wallace, apparently fed up by the messy encounter, quit the race in a fit of rage.After the "incident", Wallace took to Twitter and tried to make the best of his rage-quitting by showing that he wasn't taking it too seriously.Unfortunately, his sponsor, joint/muscle cream company Blue-Emu, was dead seriously peeved. In fact, they were so serious that they decided to pull out their sponsorship of Wallace. Ben Blessing, executive vice president of Blue-Emu was even quoted in saying : “Can you imagine if he did that in real life on a track?”Blessing also told Action Network that they thought sponsoring Wallace was a "blessing in disguise", but found out they aren't sponsoring a professional driver, but someone like "my 13-year-old son" who broke his controller while building a house in a game.Too bad for Wallace--Emu company has sponsored his real-life racing team, and just recently signed a multi-year contract to become an official partner of NASCAR.Goes to show why losing your cool and quitting halfway can make you lose a lot of money--just like that. Also Read: Leclerc to Use Same Engine in China Fast Facts about Lewis Hamilton