Selma Blair's Gorgeous Adaptable Clothing Line Is Nearly All on Sale


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Maybe it was her cool, color-blocked gown from the 2004 CFDA Awards ceremony or her lacy black-and-white number from the 2005 Mont Blanc Women’s Jewelry Collection Launch. Whatever iconic look you associate with actress Selma Blair, there’s a good chance it was created by her good friend, designer Isaac Mizrahi — and now the longtime friends have teamed up to launch a brand new clothing collection. Isaac Mizrahi Live! x Selma Blair line with QVC is not your average fashion line — it’s a universally designed clothing line inspired by Blair, who was diagnosed with multiple sclerosis in 2018 and has since become an outspoken advocate for people with disabilities.

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Now, Blair is also the QVC Brand Ambassador for Accessibility. She’s her same stylish self, just with a few adjustments to her wardrobe and a whole new perspective on dressing well. “Fashion has always been my love language and this collection is a celebration of color and thoughtful design pieces that I am excited to share,” Blair said about the Isaac Mizrahi Live! x Selma Blair line with QVC. She’s also thrilled to be working with someone she shares a personal history with. “Isaac is a longtime friend and favorite designer of mine, with equal parts style and personality — beloved by the women he has so beautifully dressed. So, when I decided I wanted to create chicer more accessible wardrobe options, I knew I had to do it with Isaac,” she added.


So what does universal design mean when it comes to clothes? In a nutshell, it means the clothes are accessible to people with disabilities, adapting to their different needs without compromising the style or integrity of the garments. To make sure their collection lived up to this promise, Blair, Mizrahi and their team worked closely with the disability community throughout the process of designing and fitting each item. The Isaac Mizrahi Live! x Selma Blair line with QVC features shirts, sweaters, jackets, pants (including wheelchair fit designs), and accessories that have accessible features like inclusive sizing (XXS-3X), easy-open neck lines, hook-and-loop closures, side-seam openings and more “for wherever we are in the arc of life.”


“I have always been a champion of inclusivity and have designed my QVC collections to make women feel beautiful and confident,” said Mizrahi of his designs with Blair and beyond. “This collaboration with Selma is a natural expression of our shared passion for style and bringing more universal fashion to the world.”


Want a closer look at what this universally designed collection has to offer? We thought you’d never ask! Here’s a handful of our favorite, red carpet-worthy looks to get your hands on from the Isaac Mizrahi Live! x Selma Blair line with QVC, which has launched with 15 pieces — and stay tuned for more to follow in November of this year and March 2024. Plus, get $20 off your first order with the code HOLIDAY20.


Our mission at SheKnows is to empower and inspire women, and we only feature products we think you’ll love as much as we do. QVC is a SheKnows sponsor, however, all products in this article were independently selected by our editors. Please note that if you purchase something by clicking on a link within this story, we may receive a small commission of the sale.


Isaac Mizrahi Live! x Selma Blair Zip Boat Neck Striped T-Shirt


The collection is packed with classics, like this black-and-white striped boat neck top. It’s a wardrobe essential that pairs perfectly with white jeans or khakis, and it’s hiding a zipper at the shoulder that makes it so much easier to take on and off than your standard pull over shirt.

Isaac Mizrahi Live! x Selma Blair Zip Boat Neck Striped T-Shirt

Price: $69 $50

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Isaac Mizrahi Live! x Selma Blair Cable Knit V-Neck Sweater


Following the theme of wardrobe must-haves is this cable knit sweater that comes in three colors including cheerful orange. A wide neck and slits at the side make the top adaptable and easy to pull on and off.

Isaac Mizrahi Live! x Selma Blair Cable Knit V-Neck Sweater

Price: $69 $50

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Isaac Mizrahi Live! x Selma Blair Faux Leather Zipper Jacket


This faux leather jacket is as chic as it gets and it’s also a pleasure for people with disabilities to rock,  thanks to a magnetic zipper closure, O-ring zipper pulls, magnetic snaps and inside chest welt pockets.

Isaac Mizrahi Live! x Selma Blair Faux Leather Zipper Jacket

Price: $119 $90

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Isaac Mizrahi Live! x Selma Blair Magnetic Button Poplin Shirt


Every wardrobe needs a basic white button down, and this poplin top fits the bill. Magnetic buttons make it a breeze to take on and off.

Isaac Mizrahi Live! x Selma Blair Magnetic Button Poplin Shirt

Price: $109

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Isaac Mizrahi Live! x Selma Blair Side Zip Pant Wheelchair Fit


These sophisticated straight leg slacks will become your go-to basic pants with so much flair. They’re designed to suit people who use a wheelchair thanks to a seated fit and flat seams for comfort, elastic waistband with apron opening, three interior pull-on loops, side zipper closure and removal of the back pockets.

Isaac Mizrahi Live! x Selma Blair Side Zip Pant Wheelchair Fit

Price: $99 $80

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