MU researchers pinpoint symptoms directly related to long COVID

Rebekah Hogan lies with her son Sebastian, 9, in the living room of their home in Troy, N.Y. April 7, 2022. The family of five, including Rebekah's husband James, a disabled military veteran, contracted COVID-19 in late 2020. Almost a year and a half later, they all suffer symptoms of long COVID. New research from the University of Missouri has pinpointed specific symptoms of"long COVID," symptoms that linger months or years after the COVID virus has left their bodies.

New research from the University of Missouri has pinpointed the symptoms of what is known as "long COVID," symptoms that linger months or years after the COVID virus has left their bodies.

What surprised researchers are that there are just seven long COVID symptoms specific to the COVID virus.

The symptoms

  • Rapid heartbeat

  • Hair loss

  • Fatigue

  • Chest pain

  • Shortness of breath

  • Joint pain

  • Obesity

Liza Fisher looks at the skyline while posing for a portrait at her home in Houston on Sept. 5, 2022.  In early July 2020, Liza Fisher of Houston was diagnosed with COVID pneumonia and by the end of the month, she was in a hospital intensive care unit. A week later, she was transferred to a rehab facility where she stayed, other than another two-week hospital stint, until Oct. 13, 2020.  In rehab she lost the ability to walk and began suffering debilitating tremors, for reasons her doctors still don't understand. Now, more than two years after her initial infection, Fisher is making slow, incremental progress and hoping for no more setbacks.

"COVID-specific long-term sequelae in comparison to common viral respiratory infections: an analysis of 17,487 infected adult patients" was published in the journal Open Forum Infectious Diseases. Sequelae is a medical term for having long-term consequences.

The research looked at the electronic medical records of 52,461 patients at 122 hospitals, with identifying information deleted.

Chi-Ren Shyu
Chi-Ren Shyu

The research looked at three categories of patients: people diagnosed with COVID but with no other viral respiratory infections, people with common respiratory infections, but not diagnosed with COVID and people with neither COVID or a viral respiratory infection, said Chi-Ren Shyu, director of the MU Institute for Data Science and Informatics.

"That's the reason for the large scale of data," Shyu said.

The analysis reviewed 47 commonly reported symptoms of long COVID.

Adnan Qureshi, MD
Adnan Qureshi, MD

Study co-author Adnan Qureshi, professor of neurology, said many of the survivors of COVID have lingering symptoms that don't allow them to resume their normal lives.

"The number of survivors continues increasing," Qureshi said. "Obviously the healthcare system has to adapt"

Pinpointing the symptoms that are specific to a COVID diagnosis will help, he said.

The seven symptoms don't surprise the researchers.

"They are not surprising to us," Shyu said. "What surprised us is there are seven instead of 20. That's the surprising part."

They don't discount health concerns others have, they said.

"People with other viral respiratory infections suffer from other symptoms," Shyu said. "It's really the purpose of this study to find out what is specific to long COVID"

Because of the large number of COVID survivors, disability and lack of productivity are increasing, Qureshi said.

"It's causing a large burden," he said. "Society needs to gear up."

The research won't end here, but must be ongoing, Shyu said.

Other co-authors were Jane Armer and William Baskett at MU and Daniel Shyu at the University of Minnesota. The study received funding from the National Institutes of Health.

Roger Mckinney is the Tribune's education reporter. You can reach him at rmckinney@columbiatribune.com or 573-815-1719. He's on Twitter @rmckinney9.

This article originally appeared on Columbia Daily Tribune: The 7 symptoms MU researchers connected with long COVID using data