I’m a Dermatologist, and These Moisturizers for Over-40 Skin Are a ‘Must’ for Fall


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As we age, our skin needs more TLC than it did in our younger years. Age brings a change in cell turnover that can result in signs of aging appearing. You know, pesky lines, wrinkles, sagging skin, and a dull and dry complexion. That’s why it’s essential to have a good moisturizer on hand. But with so many options on the market, it can be hard to decipher one that’s suited for your skin. That’s where the best moisturizers for mature skin come in. Fortunately, Target has a vast selection of ones that are a must-have for those over 40.

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When you’re shopping for a cream to add to your beauty lineup, take a look at its formula and see if it contains vitamin A. As Dermatologist Dr. Blair Murphy-Rose says, it’s “the best and most well-studied anti-aging ingredients.” Vitamin A actually has other forms, with its most popular being retinol—one of skincare’s most famous ingredients.


“Retinol has many wonderful skin benefits—it stimulates the production of collagen, supports healthy skin cell turnover, increases elasticity, treats fine lines, improves texture and tone, minimizes the appearance of pores, decreases oil and sebum production, and improves discoloration,” Dr. Murphy-Rose explains.

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Dr. Murphy-Rose also adds that water loss in the skin increases as we age, so using products to keep the skin hydrated is essential. “It is important to use a moisturizer that’s balanced for your skin type,” she notes. “Look for a combination of humectants and rich moisturizers like emollients and skin butters to bind and then lock in moisture to the skin.”


Keep scrolling to see the best moisturizers for over-40 skin.

RoC Retinol Anti-Aging + Firming Night Face Moisturizer

RoC Retinol Anti-Aging + Firming Night Face Moisturizer
RoC Retinol Anti-Aging + Firming Night Face Moisturizer


Dr. Murphy-Rose recommends RoC’s night cream, as it boasts a laundry list of benefits and contains ingredients that can help firm the skin. The formula has retinol, a skincare hero for smoothing fine lines, wrinkles, and uneven skin tone. Shoppers even say that it helps smooth dark spots, too. Reminder: Only use the cream at night and layer an SPF into your daily routine.


One reviewer shared: “I squeeze a pea-sized amount onto my finger and gently drab it around my face, especially near my chin and mouth, where I have small wrinkles from smoking. Slightly rub it in and then leave it overnight. I don’t top it off with moisturizer since it already contains Shea butter. Yes, this stuff does work! I have noticed a difference in brightness and smoothing. The pores look tighter, and I can tell the skin looks firmer.”

Retinol Anti-Aging + Firming Night Face Moisturizer

Price: $21.99

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Naturium Plant Ceramide Rich Moisture Cream

Naturium Plant Ceramide Rich Moisture Cream
Naturium Plant Ceramide Rich Moisture Cream


If you’re looking for a plant-based skincare option, look no more! Naturium’s moisturizer is packed with plant-derived ceramides, which restore the skin’s natural moisture. The result? Banished dull and dry skin.

Plant Ceramide Rich Moisture Cream

Price: $24.99

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CeraVe Moisturizing Cream

CeraVe Moisturizing Cream
CeraVe Moisturizing Cream


Dr. Murphy-Rose says that the Cerave Moisturizing Cream “is a great choice developed for sensitive skin.” It’s filled with hyaluronic acid to enhance the skin’ moisture, and ceramides that restore the skin’s barrier. Plus, the moisturizer is fragrance-free, hypoallergenic​, and oil-free so that it does not irritate the skin.

Moisturizing Cream

Price: $14.99

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Neutrogena Hydro Boost Water Gel Moisturizer

Neutrogena Hydro Boost Water Gel Moisturizer
Neutrogena Hydro Boost Water Gel Moisturizer


“This is a budget-friendly choice rich in antioxidants, including hyaluronic acid, dimethicone, and glycerin to powerfully hydrate and plump skin,” Dr. Murphy-Rose says. “It is oil-free, dye-free, paraben-free, and fragrance-free.”

Hydro Boost Water Gel Moisturizer

Price: $19.99

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La Roche Posay Toleriane Double Repair UV Moisturizer

La Roche Posay Face Toleriane Double Repair UV Moisturizer 
La Roche Posay Face Toleriane Double Repair UV Moisturizer


Not only is this daily face moisturizer dermatologist-approved, it’s also a shopper favorite. The daily moisturizer is crafted with La Roche-Posay’s Prebiotic Thermal Water, ceramide-3, niacinamide, and glycerin, which nourishes and hydrates. It also features SPF 30 to protect against damaging rays. Aside from the ingredients, the moisturizer blends into the cast without leaving a white cast behind—it’s also oil-free, so it doesn’t leave a greasy finish.

Toleriane Double Repair UV Moisturizer

Price: $21.99

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RoC Multicorrexion Crepe Repair Face and Neck Cream

RoC Multicorrexion Crepe Repair Face and Neck Cream
RoC Multicorrexion Crepe Repair Face and Neck Cream


Dr. Murphy-Rose also says to add this scream to your list if you have mature skin. The Face & Neck Anti-Aging Moisturizer has a unique blend of Hexyl-R Complex and extracts that work together to help hydrate and smooth. The brand also reports that these ingredients also fade the appearance of crepey skin and wrinkles.

Multicorrexion Crepe Repair Face and Neck Cream

Price: $24.99

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