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'The Last Ship' Trailer Exclusive: See 'Grey's Anatomy' Alum Eric Dane in Uniform

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O Captain McSteamy! My Captain McSteamy! Your fearful trip is far from done... unfortunately for "Grey's Anatomy" alum Eric Dane and the rest of the crew of TNT's "The Last Ship."

However, their misfortune spells a summer of small-screen thrills for fans of the William Brinkley novel that inspired the series... and just about anyone who likes hot boys in uniform, big guns, even bigger boats, and world-ending biological events.

On Friday, a new extended trailer for "The Last Ship" (debuting June 22) will hit select movie theaters. But why wait when you can see alums of "Grey’s," "Firefly," "Alphas," "24," and "Nip/Tuck" trying to save the human race today on Yahoo TV exclusively?

[Related: 'Lost's' Titus Welliver to Play Pivotal Role on 'The Last Ship']

As you can see in the preview above — and have come to expect from producer Michael Bay ("Transformers," "Armageddon," "Pearl Harbor," and "Black Sails") — these folks are not going down without a fight. A really big, explosive fight.

"I liked the idea of working with Michael Bay, and it's always been a genre I wanted to involve myself with," Dane said when Yahoo TV visited the Manhattan Beach set back in February. "Who doesn't want to be a captain of a guided-missile destroyer? I'm a guy. I like playing with toys and guy stuff and getting physical. It was a huge change of pace coming from 'Grey's.' I knew this was going to be physically demanding, and I come home from work some days pretty beat up, but this was something I had to do."

'The Last Ship' Trailer Exclusive: See 'Grey's Anatomy' Alum Eric Dane in Uniform

Eric Dane stars in The Last Ship, a new action-packed series coming to TNT from executive producer Michael Bay. Ph: Richard Foreman/SMPSP

"The Last Ship" follows the crew of the U.S.S. Nathan James, a Navy destroyer that had spent months running drills in radio silence in the Arctic while hosting a brilliant paleomicrobiologist (Rhona Mitra) doing research. Unbeknownst to Captain Chandler (Dane) and company, a killer virus has been running rampant and decimating most of the planet's population — including the president — and sending survivors into panic mode, throwing the economy and governments of the world into chaos.

It turns out the scientist knew more than she was letting on, and now she may be civilization's last hope for a cure; working with a crew who now doesn't trust her might be her ticket to staying alive.

[Related: How Shows Have Portrayed the End of the World]

"It's a pressure cooker until the moment I am allowed to tell him, and then it's not the best news. I have been hiding the fact that, by the way, your wife and two kids and everyone else on this ship's family has been in jeopardy for months. Oops," Mitra explained. "You have two very specific dogmatic groups of people, the scientific world and the military, and they have their different agendas. But his mission and my mission are now one and the same. It becomes this harmonious balance and this relationship building between these groups, and you see the people underneath coming out."

The Last Ship, an action-packed drama coming to TNT from executive producer Michael Bay. Ph: Richard Foreman/SMPSP

While those two worlds might be melding, it seems everything from a cigar-chomping Russian admiral (Ravil Isyanov) to what might be a gregarious gaggle of doomsday preppers to the virus itself is trying to sink Captain Chandler's battleship.

"People get desperate and the world falls apart rather quickly, and everyone left alive is worried about their families and what will happen to them," explained showrunner Hank Steinburg, who co-wrote the Jonathan Mostow-directed pilot with fellow producer Steven Kane. "But both the military personnel and the scientists have a sense of duty to try and fix it, or die trying."

"The Last Ship" premieres June 22 at 9 p.m. on TNT.