Vikings RB Dalvin Cook inactive against Seattle due to ankle injury

Sep. 26—Vikings running back Dalvin Cook, who had been listed as questionable because of an ankle injury, was inactive for Sunday's game against Seattle at U.S. Bank Stadium.

Cook was hurt in last Sunday's 34-33 loss at Arizona but remained in the game. He did not practice all week, but Vikings coach Mike Zimmer left open the possibility that he could play.

With Cook out, Alexander Mattison took over as the starter. The only other Vikings running back active against the Seahawks was Ameer Abdullah, although fullback C.J. Ham also can be used for rushing attempts.

Other inactive players for the Vikings were linebacker Anthony Barr (knee), tackle Christian Darrisaw (groin) and cornerback Harrison Hand (hamstring), quarterback Kellen Mond, defensive tackle James Lynch and defensive end Patrick Jones II.

Inactive for Seattle were wide receiver D'Dwayne Eskridge, quarterback Jake Luton, linebacker Benson Mayowa, running back Rashaad Penny, safety Marquise Blair, tackle Brandon Shell and defensive end L.J. Collier.

It marked the 22nd game Cook has missed in his five-year career. He sat out 12 in 2017 due to a torn ACL, five in 2018 because of hamstring issues, two in 2019 due to chest and shoulder injuries and two last season because of a groin injury and the death of his father.

Also Sunday, a source said the Vikings want to re-sign tackle Blake Brandel, who was waived Saturday when Abdullah was signed off the practice squad, to at least the practice squad if he clears waivers. The deadline for teams to put in a waiver claim on Brandel is 3 p.m. Monday.