Recap: Louisville loses to BC, Brock Domann takes over at QB after Malik Cunningham injury

Coming off an impressive 41-3 victory over South Florida, the Louisville football team (2-2, 0-2 ACC) hopes to secure its first ACC win of the season when it travels to Boston College (1-3, 0-2 ACC) for a 12 p.m. kickoff.

With both teams in similar positions, the Cardinals will look to win their second straight game against the Eagles. Boston College, however, has won three of the last five meetings with U of L.

Last week, Louisville showed growth in its running game. Malik Cunningham led the way with 113 rushing yards, but Trevion Cooley (75 yards on 11 carries) and Tiyon Evans (51 yards on 13 carries) also played a big part.

On defense, U of L may be challenged by Boston College wide receiver Zay Flowers, who is considered one of the best receivers in the ACC. Flowers is currently the second-leading receiver in the ACC with 330 yards and three touchdowns on 29 receptions for an average of 11.4 yards per catch.

That also puts him 35th among FBS players in yardage and 36th in yards per game with 82.5. The next closest Eagles receiver is George Takacs with 166 yards and a score on 16 catches for an average of 41.5 receiving yards per outing.

Here's how you can watch and/or listen to Louisville vs Boston College, and follow along for live updates. Once the game starts, check back in for video highlights of all the top plays.

Oct 1, 2022; Chestnut Hill, Massachusetts, USA;  Louisville Cardinals defensive back Rance Conner (18) reacts with cornerback Quincy Riley (3) after recovering a fumble during the first half against the Boston College Eagles at Alumni Stadium. Mandatory Credit: Bob DeChiara-USA TODAY Sports
Oct 1, 2022; Chestnut Hill, Massachusetts, USA; Louisville Cardinals defensive back Rance Conner (18) reacts with cornerback Quincy Riley (3) after recovering a fumble during the first half against the Boston College Eagles at Alumni Stadium. Mandatory Credit: Bob DeChiara-USA TODAY Sports

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FINAL: Boston College 34, Louisville 33

Read Louisville football writer Alexis Cubit's story from the shocking loss to Boston College.

Boston College takes the lead with a field goal - 1:56, Q4

Boston College kicker Connor Lytton gives the Eagles a slight lead over Louisville with a 26-yard field goal.

Boston College 34, Louisville 33

Brock Domann in for Louisville football after Malik Cunningham injury

Junior quarterback Brock Domann was thrust into Louisville football's game against Boston College when starter Malik Cunningham exited with an injury. Get to know Domann.

Tiyon Evans out of game for Louisville football

Louisville running back Tiyon Evans was shown in street clothes on the sidelines with a boot and crutches.

Malik Cunningham goes into the injury tent

The ACC Network broadcast showed Louisville quarterback Malik Cunningham being treated on the sidelines in the injury tent. Brock Domann is in for the Cardinals.

Boston College closes the gap against Louisville with a field goal - 7:24, Q4

Boston College kicker Connor Lytton made a 37-yard field to cut Louisville's lead down.

Louisville 33, Boston College 31

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End of the third quarter - Louisville 33, Boston College 28

Malik Cunningham throws touchdown pass to give Louisville the lead - 4:50, Q3

Louisville finished a seven-play, 75-yard drive with a 12-yard touchdown pass from Malik Cunningham to Ahmari Huggins-Bruce.

Louisville 33, Boston College 28

Zay Flowers makes another big touchdown catch for Boston College - 8:07, Q3

Boston College responds in a big way following Louisville's field goal. BC wide receiver Zay Flowers caught a 69-yard touchdown to give the Eagles the lead. Flowers has three catches for 128 yards and two scores.

Boston College 28, Louisville 26

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Louisville extends its lead over BC with a field goal - 9:03, Q3

James Turner nailed a 48-yard field goal attempt to distance Louisville a little from Boston College.

Louisville 26, Boston College 21

Boston College called for targeting Malik Cunningham; Cunningham returns

Malik Cunningham returns to the field after sitting out one play. Brock Domann handed off to Jawhar Jordan for a 2-yard gain while Cunningham was absent.

Malik Cunningham down on the field - 11:04, Q3

Louisville quarterback scrambled on 3rd and 5 and was hit by a Boston College defender as he slid to the turf. A flag was thrown on the play. Cunningham is being treated by trainers on the field.

Louisville leads Boston College at halftime, 23-21

Malik Cunningham scores his third rushing touchdown of the game - 1:00, Q2

After a couple of failed attempts at the goal line, Louisville quarterback Malik Cunningham punched in a 1-yard rushing touchdown. Cunningham has 36 yards on 11 carries and three touchdowns.

Louisville 23, Boston College 21

Louisville running back Tiyon Evans treated by trainers on field, later walks off on his own power - 1:10, Q2

Boston College takes back the lead with Alex Broome touchdown - 3:13, Q2

After a costly turnover earlier in the game, Boston College running back Alex Broome scored on a big 40-yard touchdown run.

Boston College 21, Louisville 16

Malik Cunningham puts Louisville football back on top over Boston College - 5:59, Q2

Good news: Coming off the turnover, Louisville quarterback Malik Cunningham scored on a 6-yard run. Bad news: Louisville's PAT was blocked.

Louisville 16, Boston College 14

Louisville's Monty Montgomery forces another fumble - 6:25, Q2

The U of L linebacker has done it again. This time around, Monty Montgomery rushed Boston College quarterback Phil Jurkovec, who threw the ball behind himself and the ball was recovered by YaYa Diaby.

Boston College's Zay Flowers makes incredible touchdown catch - 12:03, Q2

Wow. In double coverage, Boston College wide receiver Zay Flowers caught an impressive 57-yard touchdown from quarterback Phil Jurkovec. Boston College takes its first lead of the game.

Boston College 14, Louisville 7

James Turner gives Louisville the lead after field goal - 12:22, Q2

Louisville once again takes the lead after kicker James Turner makes a 24-yard field goal.

Louisville 10, Boston College 7

End of the first quarter - Louisville 7, Boston College 7

Monty Montgomery comes up big again for Louisville with forced fumble - 0:59, Q1

Louisville linebacker Monty Montgomery does it again. This time, he caused Boston College quarterback Phil Jurkovec to fumble.

Boston College ties it up against Louisville with a passing touchdown - 4:34, Q1

Boston College's Phil Jurkovec tossed a 1-yard touchdown to Joseph Griffin Jr. to even things up. The score was set up by an impressive 22-yard run by Zay Flowers.

Louisville 7, Boston College 7

Monty Montgomery intercepts a pass for Louisville - 7:43, Q1

Boston College was driving on Louisville, but linebacker Monty Montgomery intercepted a tipped pass to give the ball back to the Cards.

Louisville 7, Boston College 0

Louisville scores first off a Malik Cunningham touchdown - 8:51, Q1

Louisville quarterback Malik Cunningham scored his 45th career rushing touchdown off a 1-yard score.

Louisville 7, Boston College 0

Louisville vs BC prediction

Our Louisville football writer, Alexis Cubit, predicts the Cardinals will beat Boston College, 35-21. Click here to read her full analysis.

Jalen Mitchell out again with injury

Louisville running back Jalen Mitchell is out for the third straight game with a lower leg injury.

Louisville football vs Boston College weather forecast

It's a wet one in Boston today. The forecast is calling for rain most of the game, with an 80% chance at kickoff time and decreasing throughout the game. Rain is present pregame, and temperatures won't escape the low 50s.

How to watch Louisville football vs Boston College on TV, livestream

Game time: 12 p.m. ET, Saturday, Oct. 1

Location: Alumni Stadium (Chestnut Hill, Massachusetts)

TV: ACC Network

Eligible subscribers can also find the game live on Spectrum: 524, Dish: 402 and DirecTV: 612.

Online livestream: WatchESPN

Terrestrial radio broadcast: 93.9-FM/970-AM

Online radio broadcast: GoCards.com

How to watch:Louisville vs. Boston College football: Kickoff, TV channel, stream, spread

Louisville football vs Boston College spread, betting odds

Louisville is favored by 13.5 points. (Last updated Sept. 30)

Odds provided by Tipico Sportsbook. Access USA TODAY Sports’ betting odds for a full list.

This article originally appeared on Louisville Courier Journal: Louisville football vs Boston College: Cards suffer multiple injuries