LIVE: Colts vs Chiefs scores, highlights and more from NFL Week 3

The Indianapolis Colts are trying to turn things around in their home opener in NFL Week 3 action against the Kansas City Chiefs.

Colts quarterback Matt Ryan is among those who have struggled in the opening weeks. They have tied the Houston Texans and are coming off a shutout loss to the Jacksonville Jaguars. Patrick Mahomes has led the Chiefs to victories over the Arizona Cardinals and Los Angeles Chargers.

Follow Nate Atkins, Joel A. Erickson, Akeem Glaspie and Gregg Doyel as the Colts seek their first victory. We will also have score updates and highlights throughout, so please remember to refresh.

Part of the mix: Isaiah Rodgers sees the field on defense for the Colts

'I have no idea': Chiefs get a controversial 2-point conversion vs. Colts

Final: Colts 20, Chiefs 17

The Colts' first long drive of the season yields their first win.

An 8-plus minute, 76 yard drive results in Jelani Woods' winning touchdown with 24 yards left from 12 yards.

Matt Ryan completes 27-of-37 for 222 yards and two TDs to Woods. He is sacked 5 times and fumbles twice. Michael Pittman Jr. has 8 catches for 72 yards, and Alec Pierce 3 for 61. Jonathan Taylor has 21 carries for 71 yards.

Kansas City has numerous special teams blunders and crucial defensive penalty to help the Colts keep their winning drive alive.

Patrick Mahomes completes 20-of-35 passes for 262 yards, 1 touchdown, and the last-second interception. JuJu Smith-Schuster has 5 catches for 89 yards. KC runs for 58 yards.

Rodney McLeod gets the interception on the deflection.

Patrick Mahomes hits Marquez Valdes-Scantling for 24 yards into Colts territory.

Colts stop the Chiefs at the 15 on the kickoff return, but E.J. Speed is called for a person foul. The Chiefs start from their 30.

:24 left 4Q: Colts take the lead

Matt Ryan hits Jelani Woods for the second time. This one is from 13 yards. Colts 20, Chiefs 17

2:00 left 4Q: Colts try to take the lead

They have a first down at the Kansas City 29.

4:48 left 4Q: Chiefs keep Colts alive with a penalty

The Chiefs sack Matt Ryan on third down, then KC's Chris Jones says something to Matt Ryan that the officials don't like. An unsportsmanlike conduct penalty gives the Colts a first down at their 46.

6:40 left 4Q: Colts convert a 4th down

Matt Ryan sneaks it and the Colts keep possession. That's their first 4th-down conversion of the season in 6 tries. Colts are up to 200 yards of offense.

8:38 left 4Q: Colts keep hanging in there

Matt Ammendola misses a field goal from 34 yards. Colts get it back at their 24.

Patrick Mahomes hits JuJu Smith-Schuster for 53 yards, converting a 3rd-and-long. KC is in the red zone.

10:47 left 4Q: Colts fail on 4th down

Jonathan Taylor's leap on a 4th-and-short is stopped by the Chiefs. Indianapolis is 0-for-5 on 4th downs this season. KC takes over at Indy's 31.

Michael Pittman Jr. wrestles a pass from L'Jarius Sneed and gains 25 yards, putting the Colts in Chiefs territory. Pittman has 6 catches for 61 yards.

13:29 left 4Q: Chiefs fail on fake field goal

The Chiefs line up for a 42-yard field goal but try to pass out of it. Bobby Okereke keeps pressure on the receiver, and the pass from holder (and punter) Tommy Townsend is incomplete. Colts take over at their 24.

KC has a muffed punt that the Colts recovered, a missed extra point, a fumbled kickoff return (which KC recovered) and a failed fake field goal.

Entering 4Q: Chiefs are in Colts territory

Chiefs get a little tricky as Patrick Mahomes gets a rollout flea-flicker and completes a 26-yard pass to Noah Gray. KC is at the Indy 32.

2:53 left 3Q: Chase McLaughlin brings Colts closer

Colts drive close to the red zone before Jonathan Taylor is stuffed and Matt Ryan is sacked (that's No. 4). Chase McLaughlin makes a 51-yard field goal. Chiefs 17, Colts 13

7:56 left 3Q: Chiefs extend their lead on the Colts

The Chiefs have scored on their second-half opening drive in every game, but this time they have to settle for a 26-yard Matt Ammendola field goal. Drive takes up 7:04. Chiefs 17, Colts 10

Halftime: Chiefs 14, Colts 10

The Colts are keeping Patrick Mahomes largely in check, but their inability to protect Matt Ryan -- and his propensity to fumble -- leave them behind.

Both Kansas City touchdowns have come off of strip-sacks of Ryan. The Colts' TD came after a Chiefs special teams snafu.

Ryan is 11-of-17 for 83 yards and a touchdown to Jelani Woods, and he has been sacked 3 times. Jonathan Taylor has 14 carries for 41 yards. Alec Pierce has 2 catches for 47 yards.

Mahomes is 10-of-15 for 84 yards, and he has been sacked once. Travis Kelce has 3 catches for 38 yards, including a TD.

Both teams gained 102 yards on offense in the half.

1:46 left 2Q: Chiefs take the lead

Clyde Edwards-Helaire rushes in from 1 yard. Mahomes hits Travis Kelce for the 2-point conversion play. Chiefs 14, Colts 10

3:23 left 2Q: Matt Ryan loses a fumble

Carlos Dunlap forces the fumble by Matt Ryan and L'Jarius Sneed recovers at the Colts 21.

Ryan had hit Alec Pierce for a 30-yard gain on their first play from the 1.

4:46 left 2Q: Colts to start from their 1

The Colts stop the Chiefs near midfield, and KC's punt is downed deep in Colts territory.

6:41 left 2Q: Chiefs are driving

Chiefs have 2nd-and-6 at their 44 when right tackle Andrew Wylie leaves with an injury.

Yannick Ngakoue gets the Colts' first sack since the Houston game. He had been on the injury list throughout the week.

Colts safety Julian Blackmon (left ankle) leaves the game.

9:40 left 2Q: Colts drive for another score

Chase McLaughlin's first field goal try since returning to the Colts is good from 43 yards. Colts 10, Chiefs 6

Colts are shortening the game by feeding Jonathan Taylor. He has 13 carries for 40 yards.

Alec Pierce's first career reception goes for 17 yards and a first down.

:34 left 1Q: Chiefs score, but PAT misses

Patrick Mahomes hits Travis Kelce for the 3-yard TD, one play after a 29-yard connection between them. Matt Ammendola's PAT misses. Colts 7, Chiefs 6

2:37 left 1Q: Colts fail on 4th down

L'Jarius Sneed hits Matt Ryan for a sack on 4th down. Ryan fumbles, his 6th of the season, but the Colts recover. Chiefs take over at Indy's 35.

4:42 left 1Q: Colts defense has two 3-and-outs

Stephon Gilmore makes a terrific tackle to prevent Travis Kelce from converting a first down. Chiefs punt again, and the Colts take over at their 42.

Kylen Granson downs a Matt Haack punt at the Kansas City 1.

12:24 left 1Q: Colts take early lead

Matt Ryan's first completion is a 1-yard score to rookie Jelani Woods, who makes his first career catch. That's their first first-half touchdown this season. Colts 7, Chiefs 0

13:47 left 1Q: Colts recover a muffed punt

Kylen Granson pounces on the ball at Kansas City's 4-yard line after Skyy Moore of the Chiefs fails to secure the punt.

On the Colts' first drive, quarterback Matt Ryan was under heavy pressure on both his dropbacks.

1 p.m.: A lot of Chiefs fans at Lucas Oil Stadium

11:45 a.m.: Colts inactives

Colts who are inactive: QB Sam Ehlinger, CB Dallis Flowers, LB Shaquille Leonard, WR Dezmon Patmon, OT Bernhard Raimann, OT Luke Tenuta. DE Yannick Ngakoue, who was on the injury report all week, is active.

Chiefs who are inactive: RB Ronald Jones, K Harrison Butker, QB Shane Buechele, DE Mike Danna, DE Joshua Kaindoh, DE Benton Whitley, T Darian Kinnard.

Lucas Oil Stadium roof and window are open

Colts preview coverage

Insider:Colts are reeling, and the Chiefs are coming to town ... 11 things to watch

'He needs to be on the field':Isaiah Rodgers' lack of playing time for Colts is troubling

Who ya got?:Indianapolis Colts vs Kansas City Chiefs odds for NFL Week 3

This article originally appeared on Indianapolis Star: Colts vs Chiefs in NFL Week 3: Live scores, highlights, updates