Ipsen Beefs Up Pre-Clinical Oncology Pipeline With Over $850M Deal With BAKX Therapeutics

Vandana Singh
1 min read
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In this article:

  • Ipsen SA (OTC: IPSEY) and privately-held BAKX Therapeutics Inc have signed an exclusive worldwide collaboration agreement to research, develop, manufacture, and commercialize BKX-001 as a potential treatment for leukemia, lymphoma, and solid tumors.

  • Under the agreement, Ipsen will pay BAKX $14.5 million, comprising an equity investment and an upfront payment, followed by up to $837.5 million in milestone payments.

  • The companies would also share equally costs and profits.

  • BKX-001 is an oral small molecule activator of the BCL-2 associated protein- X (BAX).

  • BKX-001 binds to the trigger site of BAX in a catalytic manner, stimulating a conformational change in BAX to drive apoptosis in tumor cells.

  • Apoptosis is the naturally occurring process of programmed cell death. Deregulated apoptosis can lead to uncontrolled cell division and the development of a tumor.

  • Price Action: IPSEY stock was trading at $25.20 on Tuesday.

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