Haitian truckers had initially planned a strike to protest the shortages, but Thursday's demonstrations were largely led by motorcycle drivers angry that they could not work for lack of fuel.
Authorities also recently prohibited the sale of fuel in five-gallon containers, which has traditionally served as a mechanism for finding gasoline during shortages.
Drivers wound through the side streets of the capital on Thursday, often forced to turn around after coming across barricades. Others argued and bargained with the protesters in an attempt to let them pass.
Anger over a weakening currency, double-digit inflation, soaring crime, and graft accusations lodged against public officials have sparked violent, sometimes deadly, protests in the Caribbean island.