How To: Make a DIY Gingerbread Sugar Scrub
This year is all about self-care, so here's how to make a DIY Gingerbread body scrub ❄
Analysis of blood taken from trial participants suggests Pfizer jab can overcome number of genetic changes present within Sars-CoV-2
President-elect being urged to take strong action against likes of Facebook and Google
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Australian will join his squad next Thursday if he returns a negative result in the next round of testing
Exclusive: Flaws in rules for travellers were pointed out before they took effect
When American restaurant worker Simon Sunwoo was offered a Chinese-made COVID-19 vaccine in Shanghai this month through his employer he jumped at the chance. Sunwoo is part of China's expanding effort to get its home-grown vaccines to key workers, including restaurant workers like him, and increasingly to the general public. China is stepping up its vaccinations as several countries including Brazil, Indonesia and Turkey begin mass vaccination programmes using its vaccines.
Home Secretary says she wanted to close borders last year but appears to suggest she was overruled
Dublin, Jan. 20, 2021 (GLOBE NEWSWIRE) -- The "Global Pulmonary Arterial Hypertension (2020-2025) by Drug Class, Route of Administration, Distribution Mode, Geography, Competitive Analysis and the Impact of Covid-19 with Ansoff Analysis" report has been added to ResearchAndMarkets.com's offering. The Global Pulmonary Arterial Hypertension Market is estimated to be USD 7.4 Bn in 2020 and is expected to reach USD 9.9 Bn by 2025, growing at a CAGR of 6%.Some of the factors that impact the growth of the global pulmonary arterial hypertension market are the change in the lifestyles, rising geriatric population, and the increasing prevalence of pulmonary arterial hypertension (PAH). Several Government and private sector initiatives such as the rare disease act and the orphan drug act that create awareness and offer incentives such as tax waivers, credits, assistance & support are expected to contribute to the growth rate of the global pulmonary arterial hypertension market.However, discontinuing of drug production by major players during clinical trials and stringent regulations by Government, lack of awareness about the presence of pulmonary arterial hypertension among patients, and high diagnosis and treatment cost are expected to hinder the market growth. Technology advancements such as biomarker and new gene therapy for the treatment and advanced oral drugs create an opportunity for the market.Market Dynamics Drivers Growing Burden of Pulmonary Arterial HypertensionGovernment and Private Support for the Development of Orphan DrugsGrowing Geriatric Population Restraints Patent Expiration of Key MoleculesSide Effects Associated with the DrugsLack of Awareness among People in Developing Countries Challenges High Costs of Diagnosis and TreatmentLack of AwarenessExpiry of Patents Opportunities Advance Oral Drugs for Pulmonary Arterial HypertensionTechnology Advancements such as Biomaker and New Gene Therapy for the Treatment Segments Covered Based on Drug Class, the pulmonary arterial hypertension (PAH) market has been segmented into Soluble Guanylate Cyclase (SGC) stimulators, prostacyclin and prostacyclin analogs, phosphodiesterase 5 (PDE-5), and Endothelin Receptor Antagonists (ERA). ERA And Prostacyclin And Prostacyclin Analogs for treating PAH have the largest market share owing to the significant increase in the sales of this drug for the treatment of pulmonary arterial hypertension.Based on Distribution Mode, Online Pharmacies is expected to grow at the highest CAGR during the forecast period. An increase in preferences for e-commerce platforms and also due to the benefits provided by the online pharmacies like discounts & home delivery are fueling the growth of the market.Based on Route of Administration, the Oral Route is expected to have the largest share of the market. This is because of the wide range of benefits associated with oral drugs. The oral route is one of the simplest, most convenient, and safest routes.North America is anticipated to have a large market share due to the developed healthcare infrastructure in the developed countries like U.S. that has access to advanced therapeutics for treating PAH. Increasing awareness about Pulmonary Arterial Hypertension, a growing diagnosis rate, and supportive government initiatives resulted in an increased demand for PAH diagnosis and treatment. Europe is followed by North America. The rising geriatric population, changes in lifestyle, and exposure to pollution is anticipated to contribute toward the increasing prevalence of PAH in Europe.Some of the companies covered in this report are United Therapeutics Corporation, GlaxoSmithKline plc, Novartis International AG, AstraZeneca, Bayer Healthcare AG, Pfizer Inc., Gilead Sciences, Actelion Pharmaceuticals Ltd, Arena Pharmaceuticals, and Daiichi Sankyo Company Limited. and others.Competitive Quadrant The report includes Infogence Competitive Quadrant, a proprietary tool to analyze and evaluate the position of companies based on their Industry Position score and Market Performance. The tool uses various factors for categorizing the players into four categories. Some of these factors considered for analysis are financial performance over the last 3 years, growth strategies, innovation score, new product launches, investments, growth in market share, etc. Lions: Represents companies with a strong foothold in the market, with the highest market share, large investments in technologies, new products.Bulls: Companies that are medium in size competing with their USPs, growing companies with proven market share.Rabbits: Small companies but growing rapidly, constantly improving their offerings in the market.Tortoise: Companies that are slow in growth, having a long legacy, and stable or negative in performance. Why buy this report? The report offers a comprehensive evaluation of the Global Pulmonary Arterial Hypertension Market.The report includes in-depth qualitative analysis, verifiable data from authentic sources, and projections about market size. The projections are calculated using proven research methodologies.The report has been compiled through extensive primary and secondary research. The primary research is done through interviews, surveys, and observation of renowned personnel in the industry.The report includes in-depth market analysis using Porter's 5 force model and the Ansoff Matrix. The impact of Covid-19 on the market is also featured in the report.The report also contains a competitive analysis using the Competitive Quadrant, a Proprietary competitive positioning tool. Report Highlights: A complete analysis of the market including parent industryImportant market dynamics and trendsMarket segmentationHistorical, current, and projected size of the market based on value and volumeMarket shares and strategies of key playersRecommendations to companies for strengthening their foothold in the market Key Topics Covered: 1. Report Description1.1 Study Objectives 1.2 Market Definition1.3 Currency1.4 Years Considered1.5 Language1.6 Key Shareholders2. Research Methodology2.1 Research Process2.2 Data Collection and Validation2.2.1 Secondary Research2.2.2 Primary Research2.3 Market Size Estimation2.4 Assumptions of the Study2.5 Limitations of the Study3. Executive Summary4. Market Overview4.1 Introduction 4.2 Market Dynamics4.2.1 Drivers4.2.2 Restraints4.2.3 Opportunities4.3 Trends5. Market Analysis5.1 Porter's Five Forces Analysis5.2 Impact of COVID-195.3 Ansoff Matrix Analysis6. Global Pulmonary Arterial Hypertension Market, By Drug Class6.1 Introduction6.2 Prostacyclin and Prostacyclin Analogs6.3 Soluble Guanylate Cyclase (Sgc) Stimulators6.4 Endothelin Receptor Antagonists (ERAs)6.5 Phosphodiesterase 5 (Pde-5)6.6 Calcium Channel Blockers6.7 Others7. Global Pulmonary Arterial Hypertension Market, By Route of Administration7.1 Introduction7.2 Oral 7.3 Injectable8. Global Pulmonary Arterial Hypertension Market, By Distribution Mode8.1 Introduction8.2 Hospital Pharmacy8.3 Online Pharmacy8.4 Retail Pharmacy 9. Global Pulmonary Arterial Hypertension Market, By Geography9.1 Introduction9.2 North America9.2.1 US9.2.2 Canada9.2.3 Mexico9.3 South America9.3.1 Brazil9.3.2 Argentina9.4 Europe9.4.1 UK9.4.2 France9.4.3 Germany9.4.4 Italy9.4.5 Spain9.4.6 Rest of Europe9.5 Asia-Pacific9.5.1 China9.5.2 Japan9.5.3 India9.5.4 Indonesia9.5.5 Malaysia9.5.6 South Korea9.5.7 Australia9.5.8 Russia9.5.9 Rest of APAC9.6 Rest of the World9.6.1 Qatar9.6.2 Saudi Arabia9.6.3 South Africa9.6.4 United Arab Emirates9.6.5 Latin America10. Competitive Landscape10.1 Infogence Competitive Quadrant10.2 Market Share Analysis10.3 Competitive Scenario10.3.1 Mergers & Acquisitions10.3.2 Agreements, Collaborations, & Partnerships10.3.3 New Product Launches & Enhancements10.3.4 Investments & Fundings11. Company Profiles11.1 Gilead Sciences, Inc.11.2 United Therapeutics Corporation11.3 Novartis International AG11.4 GlaxoSmithKline Plc. (GSK)11.5 Pfizer, Inc.11.6 Dong-A ST Co., Ltd.11.7 Merck Sharp & Dohme Corp.11.8 Bayer HealthCare AG11.9 Arena Pharmaceuticals11.10 Actelion Pharmaceuticals Ltd11.11 Daiichi Sankyo Company, Limited11.12 Gilead Sciences11.13 Johnson & Johnson11.14 AstraZeneca 11.15 Bristol-Myers Squibb Company12. Appendix12.1 Questionnaire For more information about this report visit https://www.researchandmarkets.com/r/mqgah7 CONTACT: CONTACT: ResearchAndMarkets.com Laura Wood, Senior Press Manager press@researchandmarkets.com For E.S.T Office Hours Call 1-917-300-0470 For U.S./CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900
Polin Waterparks is delighted and proud to announce that its Glassy Looping Rocket, the world's first fully transparent composite waterslide, has been chosen as the winner of Best Product Innovation at the Park World Excellence Awards 2020!
One person is killed and at least 10 are injured after vehicles collide on the Tohoku Expressway.
In her new book, ‘This Is Why I Resist’, Shola Mos-Shogbamimu explores the complex intersecting nature of racism – if you’re hoping for words sugar-coated to put you at ease, look away now
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NEW YORK and LONDON, Jan. 20, 2021 (GLOBE NEWSWIRE) -- Tiziana Life Sciences plc (Nasdaq: TLSA / AIM: TILS) ("Tiziana" or the "Company"), a biotechnology company focused on innovative therapeutics for oncology, inflammation and infectious diseases, today announced its CEO and CSO, Dr. Kunwar Shailubhai, will participate in a fireside chat via a video link on Thursday 21 January 2021 at 3 pm ET / 8 pm GMT to provide updates on the Company. Date:Thursday 21 January 2021Time:3 pm U.S. Eastern / 8 pm GMTWebcast:https://b-riley-oncology-investor-conference.events.issuerdirect.com/signup About Tiziana Life SciencesTiziana Life Sciences plc is a UK biotechnology company that focuses on the discovery and development of novel molecules to treat human disease in oncology and immunology. In addition to Milciclib, the Company is also developing Foralumab for liver diseases. Foralumab is the only fully human anti-CD3 monoclonal antibody in clinical development in the world. This Phase 2 compound has potential application in a wide range of autoimmune and inflammatory diseases, such as nonalcoholic steatohepatitis (NASH), ulcerative colitis, multiple sclerosis, type-1 diabetes (T1D), Crohn's disease, psoriasis and rheumatoid arthritis, where modulation of a T-cell response is desirable. The company is accelerating development of anti-Interleukin 6 receptor (IL6R) mAb, a fully human monoclonal antibody for treatment of IL6-induced inflammation, especially for treatment of COVID-19 patients. For further enquiries: United Kingdom Investors: Tiziana Life Sciences plcGabriele Cerrone, Chairman and Founder+44 (0)20 7495 2379 United States Investors: Dave GentryRedChip Companies Inc.Office 1 800 RED CHIP (733 2447)Cell 407-491-4498 (USA)dave@redchip.com
Infosys (NYSE: INFY), a global leader in next-generation digital services and consulting, today announced the launch of Infosys Cortex, its customer engagement platform. The platform leverages technology from Genesys, a global leader in cloud customer experience and contact center solutions, along with Contact Center AI services from Google Cloud and its managed artificial intelligence (AI) and analytics services.
Forty years ago, on January 20, 1981, Ronald Reagan was sworn in for the first time as president of the United States. He faced turmoil at home and abroad: His Democratic predecessor, Jimmy Carter, had presided over the worst recession since the Great Depression, staggering rates of inflation and unemployment, the Soviet invasion of Afghanistan, the Iran hostage crisis, and a mood of defeatism and exhaustion in the aftermath of the Vietnam War and Watergate. Despite all this, Reagan laid out a bracing vision of American renewal in his inaugural address. In language both plain and stirring, he appealed to the “moral courage of free men and women,” asking Americans to rededicate themselves to noble purposes. Rejecting the dreary politics of national self-loathing practiced by the Left, he revived the concept of American exceptionalism to unite and embolden a dispirited citizenry. Though Carter’s campaign against Reagan devolved into personal attacks, Reagan never responded in kind. He thanked Carter, sitting stone-faced behind him, for offering “gracious cooperation in the transition process.” In a stunning reminder of how profoundly America’s political culture has changed, he said to Carter: “Mr. President, I want our fellow citizens to know . . . you have shown a watching world that we are a united people pledged to maintaining a political system which guarantees liberty to a greater degree than any other.” Reagan never missed an opportunity to educate the world about America’s democratic achievements. Anticipating a rising tide of identity politics and tribalism, Reagan defended the common good. He lauded the American democratic ethos that, in times of crisis, knows no ethnic or racial divisions. “All of us together, in and out of government, must bear the burden,” he said. “The solutions we seek must be equitable, with no one group singled out to pay a higher price.” The key was to recover a vibrant, dynamic free-market economy. This objective — not massive government spending and tax increases — was the surest path to providing “equal opportunities for all Americans with no barriers born of bigotry or discrimination.” Though it’s easy to forget at this historical distance, Reagan spoke to the populist and egalitarian impulses that continue to shape American political life. He decried the stagnant economy that “crushes the struggling young and the fixed-income elderly alike” and “threatens to shatter the lives of millions of our people.” The unemployed, he said, had been plunged into “human misery” and “personal indignity,” while those who work faced a punitive tax system that harassed them and held them back. Reagan praised ordinary citizens — the “men and women who raise our food, patrol our streets, man our mines and factories, teach our children, keep our homes, and heal us when we’re sick: professionals, industrialists, shopkeepers, clerks, cabbies, and truck-drivers” — for their quiet courage in serving others. This was more than campaign rhetoric; it was an outlook on American civic life forged from the experiences of being born into a poor family in a small Midwestern town, living through the Great Depression, and witnessing the nation’s resilience during the Second World War. In one moment, Reagan declared that “government is not the solution to our problem; government is the problem.” In the next, he pledged that “your dreams, your hopes, your goals are going to be the dreams, the hopes, and goals of this administration, so help me God.” Long before George W. Bush coined the term “compassionate conservatism,” Reagan envisioned a government in partnership with its citizens, one ready “to stand by our side, not ride on our back.” Together, they would care for the neighbor in need: “We shall reflect the compassion that is so much a part of your makeup,” he said. “How can we love our country and not love our countrymen; and loving them, reach out a hand when they fall, heal them when they’re sick, and provide opportunity to make them self-sufficient so they will be equal in fact and not just in theory?” It is worth remembering that Reagan began his political journey as a Democrat and voted four times for Franklin Roosevelt. As he saw it, however, the party of FDR had gradually abandoned the concept of personal responsibility for the false security of the paternalistic state. Here, perhaps, was his attempt to realize, on conservative terms, a political society that takes care of its most vulnerable. For the first time in American history, the inauguration event was held on the west side of the Capitol, thus facing the direction that had always symbolized the American future. (“We go westward as into the future,” wrote Thoreau, “with a spirit of enterprise and adventure.”) Looking out over the crowd of half a million people, Reagan could see the monuments to Washington and Jefferson. Beyond the Reflecting Pool sat the Lincoln Memorial, the marble temple of the Great Emancipator, the man who embodied both the tragedy and nobility of the American story like no other. Reagan’s simple tribute seems deeply relevant in our age of rage: “Whoever would understand in his heart the meaning of America will find it in the life of Abraham Lincoln.” Gazing beyond the monuments, Reagan drew attention to the graves at Arlington National Cemetery, representing “only a tiny fraction of the price that has been paid for our freedom.” He praised the American heroes who fought and died at the Argonne, Omaha Beach, Guadalcanal, Pork Chop Hill, “and in a hundred rice paddies and jungles of a place called Vietnam.” The reference to Vietnam touched a nerve: Reagan despised the Left for treating Vietnam veterans with contempt; he was determined to valorize them instead. America would be prepared to defend its democratic way of life on the world stage, Reagan declared, just as it always had done. “As for the enemies of freedom . . . they will be reminded that peace is the highest aspiration of the American people. We will negotiate for it, sacrifice for it; we will not surrender for it, now or ever.” The principle of “peace through strength,” important from the earliest days of his political life, would undergird his entire foreign policy. The world was already getting the message, too: Historians debate the circumstances, but even as Reagan spoke the Iranians were putting their 52 American hostages on a plane home. Reagan’s liberal critics were wrong about him and about nearly every important political issue on which they opposed him: the dynamism of free-market capitalism, the power of democratic ideals, the nature of Soviet communism, the strategy for peacefully ending the Cold War. The progressive Left, to this day, remains in a state of denial about the man and his achievements. Some conservatives, too, seem to have forgotten Reagan’s political and moral insight. They have no memory of the fearsome cultural opposition he faced — or how he overcame it. They deride those who seek a return to his political philosophy, accusing them of dispensing “Reagan bromides” and engaging in nostalgia to evade present-day realities. Yet, as Reagan liked to say, “facts are stubborn things.” After his first term in office, with the American economy roaring back to life and the Soviet Union in steep decline, he won a second term, prevailing in 49 out of 50 states — one of the greatest electoral landslides in American political history. Behind these facts are lessons for the intellectually curious. Like no other political leader, Reagan united all of the major currents of modern conservatism: free-market economics, individual responsibility, limited government, a strong national defense, patriotism, populism, civic virtue, and faith. He made American exceptionalism his lodestar. Viewed objectively, his oratory — his natural eloquence, historical awareness, and moral clarity — rivals that of the greatest statesmen of the last century. Reagan neither bullied the American people nor treated them as hapless victims. He proved that the best way to move hearts and minds was to articulate a political philosophy: clearly, compellingly, and with a touch of humor that could disarm even his toughest critics. Reagan wrote the first draft of his inaugural address and made sure that every line bore his imprint. He closed the speech with a story about sacrifice for a noble cause. As he quoted from the diary of Martin Treptow, an American soldier in the First World War, his voice cracked with emotion: “America must win this war. Therefore I will work, I will save, I will sacrifice, I will endure, I will fight cheerfully and do my utmost, as if the issue of the whole struggle depended on me alone.” In the aftermath of last week’s riot in the Capitol, it is blindingly clear that the promise of America — the concept of government by consent of the governed — is under attack. Thus, Reagan’s vision is needed more than ever. Indeed, the outcome of this struggle depends upon its revival: on ordinary Americans, united by their love of country, fighting to preserve the world’s most daring experiment in human freedom.
A pandemic that has killed more than two million people worldwide and the threat of insurrectionist violence will make today’s presidential inauguration of Democrat Joe Biden unlike any inauguration in American history. There will be no massive crowds, and likely no debates over crowd size. The National Mall will be closed to the public. And to prevent the spread of COVID-19, the traditional inaugural parade will be replaced by a celebrity-filled virtual event. There are 25,000 National Guard troops in Washington D.C., which has become a maze of fencing, concrete barriers and check points. They are there to discourage and prevent violence on the heels of the January 6 riot at the U.S. Capitol by a mob of supporters of President Donald Trump, who has refused to accept defeat and has continued to repeat baseless allegations that the November election was stolen from him through fraud. The FBI is doing additional screening of all of the National Guard troops in D.C. in an attempt to root out any members who could pose a threat, the Associated Press reported. Thousands of troops are also guarding statehouses across the country. Another difference with this year’s inauguration: the outgoing president will not be there. Trump, who is expected to depart D.C. for Florida at 8 a.m., will be the first president in more than 150 years to skip his successor’s inauguration. The last was Andrew Johnson, another impeached president, who didn’t attend the inauguration of Ulysses Grant, according to the White House Historical Association. Biden has said it is “a good thing” Trump isn’t attending. The inauguration events are expected to kick of at 10 a.m. with a virtual “Inaugural Celebration for Young Americans.” Biden is expected to arrive at the U.S. Capitol at 11 a.m., and will be sworn in as the nation’s 46th president at noon. Biden will be sworn in on the west front of the U.S. Capitol building, which is surrounded by a seven-foot-tall fence. Former presidents Barack Obama, George W. Bush, and Bill Clinton are expected to attend with their wives, as is Vice President Mike Pence. Pop star Lady Gaga is slated to perform the National Anthem, and Jennifer Lopez is scheduled for a musical performance, according to the Presidential Inaugural Committee. Country music star Garth Brooks also is expected to perform. The star power at Biden’s inauguration is in stark contrast to Trump, who struggled to recruit top-tier performers for his inauguration. “This is a great day in our household. This is not a political statement, this is a statement of unity,” Brooks said during a press conference Monday, according to several media reports. “This is history, and it is an honor to get to serve.” After he is sworn in, Biden is expected to participate in a Pass in Review ceremony, a military tradition that reflects the peaceful transfer of power to a new president. Biden, Vice President-elect Kamala Harris and their spouses will then head to Arlington National Cemetery for a wreath-laying ceremony at the Tomb of the Unknown Soldier. Biden will then receive a military escort to the White House. The virtual “Parade Across America” at 3:15 p.m. will be hosted by actor Tony Goldwyn, a Biden supporter who played the president on the television show “Scandal.” The virtual parade will feature planned appearances by comedian Jon Stewart, Olympic athletes, marching bands and dance groups. Curiously, it also will feature a performance by the reunited alt-rock band New Radicals, a one-hit wonder from the late 1990s, and an appearance by Nathan Apodaca, who gained Tik Tok fame last year after he recorded himself skateboarding to work with a bottle of cranberry juice while listening to Fleetwood Mac. The Idaho Falls native was living in a Walmart parking lot at the time, but has since bought a house after receiving a flood of donations. The inaugural events will conclude with a primetime television special hosted by Tom Hanks, and featuring performances by Jon Bon Jovi, Demi Lovato, Justin Timberlake and others. The special will be carried by most of the largest TV networks. There was no similar event four years ago celebrating Trump’s inauguration. In addition to the pomp and circumstance, Biden also is expected to implement a series of day one executive actions, including ending Trump’s restriction on immigration from Muslim-majority countries, rejoining the Paris climate accords, extending a pause on student-loan payments, and mandating masks on federal property and during interstate travel. He also has promised to “cancel” the Keystone pipeline on his first day in office.
Jennifer Lopez and Chrissy Teigen are also fans