Dallas Cowboys at New York Giants: Predictions, picks and odds for NFL Week 3 matchup

Two longtime NFC East foes do battle under the spotlight of Monday Night Football when Ezekiel Elliott's Dallas Cowboys travel to New York to face Saquon Barkley and the Giants.

How will backup quarterback Cooper Rush, who picked up a Week 2 win against the Cincinnati Bengals, fare in his second game in relief of QB Dak Prescott? Can Daniel Jones and the Giants offense get things going at home against a Dallas defense anchored by Micah Parsons? The game is set to kick off Monday at 8:15 p.m. from MetLife Stadium.

Here's a look at the betting details and USA TODAY's NFL staff picks for the Cowboys vs. Giants Week 3 game:

Cowboys at Giants odds, moneyline and over/under

• Spread: Giants (-0.5)

• Moneyline: Giants (-115); Cowboys (+103)

• Over/under: 39.5

• More odds, injury info for Cowboys vs. Giants

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NFL Week 3 odds, predictions and picks

Steelers vs. Browns | Saints vs. Panthers | Texans vs. Bears | Chiefs vs. Colts | Bills vs. Dolphins | Lions vs. Vikings | Ravens vs. Patriots | Bengals vs. Jets | Raiders vs. Titans | Eagles vs. Commanders | Jaguars vs. Chargers | Rams vs. Cardinals | Falcons vs. Seahawks | Packers vs. Buccaneers | 49ers vs. Broncos | Cowboys vs. Giants

Lorenzo Reyes: Cowboys 23, Giants 18

While the Giants have shown they’re much better this season under Brian Daboll, I’m still not sold they can be consistent. On the other side, Cooper Rush can keep this offense afloat and Micah Parsons and that pass rush will disrupt New York. The Cowboys are 8-2 against the spread in their last 10 against the Giants.

Safid Deen: Giants 23, Cowboys 20

Giants coach Brian Daboll is off to a 2-0 start with close wins over Tennessee and Carolina, as quarterback Daniel Jones is taking to coaching and running back Saquon Barkley has had a revival in a new offense. The Cowboys had a great game plan to beat the Bengals last week, but backup quarterback Cooper Rush’s luck won’t carry over in New York this week. The Giants move to 3-0, while the Cowboys fall to 1-2 in this one.

Lance Pugmire: Cowboys 16, Giants 14

They’ve found a way to win early for new coach Brian Daboll, and now the Giants eye the opportunity to reach 3-0 on Monday night against the hated Cowboys, minus Dak Prescott. Expect Saquon Barkley’s earnest running to prove decisive.

Jarrett Bell: Cowboys 23, Giants 17

Nate Davis: Cowboys 19, Giants 17

Tyler Dragon: Giants 20, Cowboys 17

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• All players

• Quarterback

• Running back

• Wide receiver

• Tight end

• Tackle

• Guard

• Center

• Kickers

• Edge rusher

• Safety

• Cornerback

• Linebacker

• Interior defensive linemen

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This article originally appeared on USA TODAY: Dallas Cowboys at New York Giants: Game odds, picks, predictions