Regular fish oil use may harm those with healthy hearts

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Regular use of fish oil supplements could increase the risk of first-time heart disease and stroke among those with good heart health, new research suggests. Photo by Adobe Stock/HealthDay News

Folks regularly taking fish oil supplements might not be helping their health as much as they might think, a new study suggests.

Regular use of fish oil supplements could increase the risk of first-time heart disease and stroke among those with good heart health, new research suggests.

However, the long-term study also found that fish oil can help those whose hearts are already in trouble, potentially slowing the progression of heart problems and lowering the risk of death.

Healthy people taking fish oil supplements had a 13% increased risk of developing atrial fibrillation, a heart rhythm problem that increases the risk of heart attack and stroke, researchers found.

They also had a 5% increased risk of stroke, results show.

"Our findings suggest caution in the use of fish oil supplements for primary prevention because of the uncertain cardiovascular benefits and adverse effects," wrote the research team led by Dr. Hualiang Lin, an epidemiologist with Sun Yat-Sen University in Guangzhou, China.

But in those with existing heart disease, regular use of fish oil lowered risk of a heart attack due to atrial fibrillation by 15%, and the risk of heart failure leading to death by 9%.

"Regular use of fish oil supplements might have different roles in the progression of cardiovascular disease," based on whether someone already has heart problems, the researchers suggested.

"Overall, I would say that the days where people just go to the store and buy buckets of fish oil pills to keep them well should be over, but fish oil may still have a role in people who are already sick," Dr. Andrew Freeman, director of cardiovascular prevention and wellness at National Jewish Health in Denver, told CNN.

When it comes to fish oil, "the devil is in the details," neurologist Dr. Richard Isaacson, director of research at the Institute for Neurodegenerative Diseases in Boca Raton, Fla., told CNN.

"First, we recommend testing for omega-3 fatty acid levels -- there are finger-prick tests you can buy online which are accurate -- and then you should continue to test. You don't want to take fish oil if you don't need it," he stressed.

Isaacson recommended getting omega-3 fatty acids from food and added that sardines and wild-caught salmon are the best sources. Farm-raised salmon is not the best choice, he said, because of impurities in the water in which they are raised.

Fish oil remains a rich source of omega 3 fatty acids, which are thought to help both heart and brain health. As such, health experts recommend that people eat oily fish like salmon at least once a week or use fish oil supplements, researchers said in background notes.

For the study, the team analyzed data from nearly 416,000 people ages 40 to 69 participating in a large-scale health study in the United Kingdom. These people were surveyed between 2006 and 2010 to gather basic health information, including their regular diet and supplement use.

Nearly a third (32%) said they regularly use fish oil supplements.

The research team then tracked the health of participants for an average of nearly 12 years, watching to see how many died, developed heart problems or suffered a stroke.

The findings were published Tuesday in the journal BMJ Medicine.

"Further studies are needed" to figure out why fish oil might not be helpful for healthy people, but useful in people with heart problems, the researchers concluded in a journal news release.

More information

The Cleveland Clinic has more about fish oil supplements.

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