Less than two weeks after a tornado killed dozens of people in Moore, Okla., Oklahomans were hit by more violent weather that killed at least two people, flipped trucks on interstate highways and mired cars in deep floods during rush hour.
Videos from the storms showed funnels sweeping the landscape -- possible tornadoes.
The stormy weather was blamed for the deaths of a mother and her baby near Interstate 40, Oklahoma Highway Patrol Trooper Betsy Randolph told ABC News.
"We know that the storm picked them up and swept them away," Randolph said. "When the troopers found them, they were both deceased.
"We know that a mother and a child were killed tonight on I-40 in Canadian County," Randolph said. "I cannot stress to you just how important it is that if people don't have to be out, that they stay inside and seek shelter. ... There's just no safe place to be except underground when a tornado is present."
Randolph said the area roads were extremely congested.
"Several spots are impassable whether it's high water or power lines that are down," she said. "We've had multiple crashes, some of which are probably going to be there for a while as we're unable to get wreckers to clear the roadway."
Local hospitals reported receiving at least 38 patients, five critical, with two fatalities among them.
Integris Health Southwest, which had three hospitals in the area, reported most of the patients. Oklahoma University Medical Center, the only level 1 trauma center in the state, reported two patients in the emergency department whose conditions were unclear.
The National Weather Service earlier had issued a tornado emergency for the Oklahoma City metropolitan area, including Moore, which is south of the Oklahoma City, amid the massive storm.
Gov. Mary Fallin told ABC News that there were power outages, flooding and flipped trucks on interstates amid apparent tornados, but the full extent of the damage was not immediately clear.
"We're real concerned about the people that are on the highways," Fallin said, noting the worst of the storm hit during the evening rush hour.
"It hit during a time when people were getting off work," Fallin said. "They knew the storms where coming in, so people were going home."
"We're seeing, right now, a lot of flooding," said Oklahoma Emergency Management spokeswoman Kelli Cain. "That is a big issue. We're seeing a lot of power issues. There's still a lot of hail. There's still safety issues out there. We haven't had a chance to get very much information about damage. There are still safety issues. It's still difficult to assess what damage is out there. We may not have information about that until tomorrow. We still have storms moving through the state."
ABC News' Ginger Zee reported seeing "multiple tornadoes with multiple vortices."
ABC News affiliate KOCO in Oklahoma City reported that an apparent tornado had touched down near El Reno, Okla., and moved east toward Oklahoma City.
"It's really bad and lightning and all the roads are flooded," said Addie Pendarvis, who works at a Sonic drive-in diner in El Reno. "It was hailing really bad earlier, too."
"We have reports of cars overturned," said ABC News' Mike Boettcher, who was monitoring police reports from his home in Oklahoma City. "People are now going out trying to find out how severe the damage is. The problem is it's widespread."
The latest storms hit less than two weeks after a tornado outbreak in Moore, Okla., killed 24 people, smashed hospitals and schools and caused widespread damage.
Moore City Manager Steve Eddy, driving around Moore after the latest storm, told ABC News this evening he saw minor flooding, power outages, but he did not immediately see evidence of tornado activity.
Oklahoma City Police Emergency Management said it was in the early stages of assessing damage. Emergency responders were helping motorists stranded by widespread flooding, but the agency said there was no confirmed touchdown of a tornado in the city.
Police in Norman, Okla., said there had been no tornados in that city.
ABC News' Dan Childs, Erin Koehane, Michael Kreisel and Wendy Fisher contributed to this report.