Week 5 fantasy injury report: Odell Beckham Jr. fractures ankle

A week after a few devastating injuries, the woes continued in Week 5, with multiple big names going down. The biggest one, by far, came at the end of the early games: Odell Beckham Jr. was carted off the field in tears with a fractured ankle, one of four Giants wide receivers to leave the game. As always, this list will be added to as injuries occur, with analysis and updates coming on a rolling basis.

Odell Beckham Jr., WR, New York Giants

Beckham Jr. is headed for surgery, according to Jordan Raanan of ESPN. It’s obviously a gigantic loss for any fantasy team and especially so for the Giants. Where do you go now? Well, as you’ll see below, it’s not as if the rest of New York’s receiving corps can be a huge help at the moment. Monitor Beckham Jr.’s outlook — as well as the other Giants wide receivers’ injuries — to see what you can salvage here.

Viewer discretion is advised for this one:

Brandon Marshall/Sterling Shepard/Dwayne Harris, WRs, New York Giants

Marshall was carted off with an ankle injury. That would be good news for those with Shepard on their team, but he also left with an ankle injury. The hits just don’t stop coming for the Giants, who have been awful out of the gates this year. Both players were initially ruled as questionable to return, though neither did. It really didn’t look good for Marshall, who was in significant pain. Shepard, at the very least, was able to limp off under his own power.

Marshall’s injury in particular opens the door for rookie first-rounder Evan Engram. He’s a terrific athlete with good size, like Marshall. He’s also been very consistent through the first quarter of the season. Add Engram if he’s available — he’s unowned in 30 percent of leagues.

Harris, who is mostly a special teams guy, broke his foot, leaving the Giants with one wide receiver by the end of the game: Roger Lewis. Lewis, who scored a touchdown on Sunday, looks to be a must-add as his fellow wide outs are dropping at an insane rate. Shane Vereen, a receiving specialist out of the backfield, is also a likely candidate to emerge as a popular target for Eli Manning.

DeVante Parker, WR, Miami Dolphins

Like Clay, Parker is a great talent who was starting to put it together at the beginning of this season. But an ankle injury forced the third-year wide out from Louisville to the locker room, and he didn’t return.

Jakeem Grant, a speedy 5-foot-7 return specialist, saw a big increase in playing time. Jarvis Landry has always been a PPR machine, and that’s certainly not changing. Deep threat Kenny Stills could be the guy who gains the most from Parker’s absence, though, as he should see more of those deep targets coming his way if Parker misses time. Jay Cutler remains way off the fantasy radar, and we’re still waiting for this offense to show much of anything.

Charles Clay, TE, Buffalo Bills

Clay, one of the most pleasant early-season surprises, went down with an unsightly injury:

The Bills officially said Clay is questionable to return with a knee injury, but Clay was carted back into the locker room, unable to put any weight on the leg.

It’s a really unfortunate turn for Clay, who has been playing some of the best football of his career. The talented veteran was coming off a five-catch, 112-yard performance against the Falcons and has been a huge part of the Bills’ passing attack, especially with Jordan Matthews struggling with his own injury issues.

If Clay’s injury is a long-term thing, there are big ramifications for the Bills. Clay is Tyrod Taylor’s go-to guy, and the Bills use multiple tight ends pretty often — and not only in running situations. So Nick O’Leary becomes an immediate candidate as he slides into the de-facto top tight end in Buffalo. Converted quarterback Logan Thomas will also see an uptick in playing time.

But perhaps the biggest benefactor from a fantasy perspective is LeSean McCoy. Shady will see a lot more of the underneath and medium-depth looks — ranges Taylor loves to target.

Bilal Powell, RB, New York Jets

It’s always been a health issue for Powell. After a huge game last week, Powell saw just a couple of carries before leaving with a calf injury for the 3-2 Jets. Once Matt Forte returns, he’s worth a look based on Powell’s health, but the best candidate would be rookie Elijah McGuire. Just based on the numbers in the backfield, McGuire, who saw 13 touches on Sunday, is worth a spot on your roster. Powell’s a solid contributor when healthy, but he’s appeared in all 16 games just twice since coming into the league in 2011.

Read more NFL coverage from Yahoo Sports:
• CBS clarifies report on Kaepernick standing for anthem
• Vice president leaves Colts game over anthem ‘disrespect’
• Big Ben throws 5 INTs after calling teammate a ‘distraction’
• Beckham Jr. carted off in tears after ugly ankle injury