Most of ‘Grey’s Anatomy’ cast will be rooting for the Chiefs in Super Bowl LVIII

Uh-oh, there could be trouble brewing on the set of “Grey’s Anatomy.”

The 20th season of the medical drama will premier next month, and it turns out most of the cast are Chiefs fans. In fact, you can add actress Ellen Pompeo to that burgeoning list of celebrity Chiefs supporters.

But not everyone on “Grey’s Anatomy” will be pulling for the Chiefs in Super Bowl LVIII. Actor Harry Shum Jr. (who fans may know best from “Glee”) is a big fan of the San Francisco 49ers.

Shum has shared messages of support for the 49ers on his Instagram account, including a video with actor Anthony Hill. It’s from the set of “Grey’s Anatomy” and shows Hill, who grew up in Kansas City, Kansas, supporting the Chiefs. Shum then shows his 49ers colors.

Hill and Shum clearly had fun with this.

Here’s the most interesting part of that social-media post: Pompeo, who portrays Dr. Meredith Grey and is an executive producer, responded with a message for Shum.

Pompeo wrote: “you know I LOVE YOU ...BUT listen up fam ....we have a problem....we are Swifties....sorry I meant Chiefs fans over here at @greysabc... we are going to have to talk. Sincerely, your boss.”

She added a laughing emoji, so it was all in good fun. But it does seem that many members of the “Grey’s Anatomy” cast are Taylor Swift fans, which means they’ll be cheering for her boyfriend, Chiefs tight end Travis Kelce, in the Super Bowl.