Shares of ImmunoGen (NASDAQ: IMGN) surged 30% on Tuesday after the biotech announced promising clinical trial results for its experimental ovarian cancer therapy, mirvetuximab. The trial was designed to assess the safety and efficacy of mirvetuximab in patients with a form of platinum-resistant ovarian cancer who were already treated with Avastin (bevacizumab), a leading therapy developed by Roche-owned Genentech. "Despite advances in the platinum-sensitive setting, most patients with ovarian cancer eventually develop platinum-resistant disease, for which there are limited treatment options, especially for those patients who have previously received bevacizumab," co-principal investigator Robert Coleman said in a press release.
Our goal is to create a safe and engaging place for users to connect over interests and passions. In order to improve our community experience, we are temporarily suspending article commenting
The former couple announced their separation after 16 years together.
- CBS News
Brianna Kupfer was found dead on the floor of the store minutes after she had sent an ominous text message to a friend, police said.
- USA TODAY Sports
New York Islanders defenseman Zdeno Chara felled Philadelphia Flyers forward Zack MacEwen with a hard punch but checked to make sure he was fine.
- The Guardian
The Steelers quarterback is headed to the Hall of Fame. But he was unloved outside Pittsburgh for understandable reasons Ben Roethlisberger almost certainly played his final game in the NFL on Sunday. Photograph: Ed Zurga/AP Ben Roethlisberger is lucky that football legacies are not decided by finales. If Sunday night was indeed Big Ben’s last ever NFL game, as he has strongly hinted, it wasn’t exactly a mic drop. In the 42-21 beatdown by the Chiefs, Roethlisberger struggled with rollouts, and l
Kate Middleton and Prince William might be moving to Windsor into one of the Queen's extra homes—get updated here.
The actress posted Instagram shots that were reminiscent of her role in the 2002’s cult classic Blue Crush
- The Telegraph
Emma Raducanu 'has a lot to learn': Sloane Stephens hits out at British No 1's behaviour after Australian Open defeat
Emma Raducanu still “has a lot to learn”, said her defeated first-round opponent Sloane Stephens, who sounded aggrieved at the way Raducanu had challenged her verbally at the start of their first-round match.
The super-sexy Savage x Fenty collection drops January 20
- Yahoo Life
Amy Schumer displays body confidence in swimsuit after liposuction, endometriosis surgeries: 'I feel good. Finally.'
The comedian's fans are praising her for being so transparent about her health journey.
- Knox News | The Knoxville News-Sentinel
Here's what happened in the second half that led to four technicals for Tennessee, Vanderbilt basketball
Here's a look at what happened between the Tennessee Vols and the Vanderbilt Commodores in the second half that resulted in four technical fouls.
UK man pleads guilty to exploiting a worker who lived in a garden shed for 40 years with no light or heating
Officers investigating Peter Swailes, 56, said his dog had better living quarters than the vulnerable worker who lived on his property.
Jake Paul celebrated his 25th birthday by posing nude with his girlfriend Julia Rose, and also made a list of goals he aims to accomplish in his 25th year.
The IRS has good news for retirees starting in 2022: you can now keep more money in your tax-deferred retirement accounts thanks to lower required minimum distributions (RMDs). For the first time in 20 years, the Internal Revenue Service has … Continue reading → The post Good News for Retirees: RMD Formula Changing for First Time in Decades appeared first on SmartAsset Blog.
- Business Insider
Dozens of former Trump officials including John Kelly and Stephanie Grisham are formulating plans to thwart their former boss in 2022 and 2024
Miles Taylor, a Trump official turned prominent anti-Trump critic, led a conference call with former officials, and told CNN that the participants were "overflowing with ideas" on how to stop Trump.
- USA TODAY Sports
Dak Prescott should be ashamed of himself – and not because of squandering the final seconds off the clock in Cowboys' wild-card playoff loss.
The Duke and Duchess of Cambridge joined forces to highlight one of Kate's most important causes
Olivia Culpo posted a playful jab on her Instagram account after she was asked to put more clothing on for a recent American Airlines flight
The mogul's latest swimsuit shots have her fans doing some deep-dive detective work
The LA Coliseum track has drawn the most comparisons to the ancient Bowman Gray Stadium in Winston-Salem, N.C.
- Yahoo Sports
The Pistons voided a traded last week after Bol failed a physical. He's reportedly slated to have foot surgery.