ST. LOUIS - Rookies in the post-season, the Washington Nationals played like poised veterans.
The Nationals escaped a bases-loaded jam in the seventh inning, pinch hitter Tyler Moore blooped a two-out, two-run single in the eighth and Washington beat the defending World Series champion St. Louis Cardinals 3-2 Sunday in an NL playoff opener.
The Nationals, who had never come close to making the playoffs since moving from Montreal for the 2005 season, overcame a wild start by 21-game winner Gio Gonzalez.
Reliever Ryan Mattheus needed just two pitches to bail out the Nationals in the seventh with St. Louis ahead 2-1. Tyler Clippard worked around an error in the eighth and Drew Storen saved it with a 1-2-3 ninth.
The NL East champion Nationals led the majors with 98 wins this season, and brought post-season baseball to Washington for the first time since 1933. The Nats go for a 2-0 series lead Monday when Jordan Zimmermann opposes Jaime Garcia.
The Cardinals made it to the best-of-five division series by beating Atlanta in the wild-card matchup Friday. But St. Louis wasted a 10-strikeout gem by Adam Wainwright, failing to capitalize enough on Gonzalez's career high-tying seven walks and frustrating its towel-waving fans.
A standing room crowd of 47,078, among the largest at 7-year-old Busch Stadium, bundled up for a game that began in 54-degree chill and featured kaleidoscope late-afternoon shadows that bedeviled hitters for several innings.
Rookie shortstop Pete Kozma misplayed Michael Morse's grounder for an error to open the eighth and set up the Nationals' go-ahead rally. Ian Desmond followed with a single off Mitchell Boggs for his third hit of the game, putting runners at the corners.
Danny Espinsoa sacrificed, leaving runners at second and third, and Kurt Suzuki struck out. In a series of moves, the Nationals sent up Chad Tracy to pinch hit, the Cardinals switched to lefty Marc Rzepczynski and Washington subbed in Moore, who had two of their three pinch homers this season.
Moore poked an outside pitch to right field and both runners scored easily.
Wainwright became the first Cardinals pitcher to reach double digits in strikeouts since Bob Gibson also fanned 10 to beat the Tigers in Game 4 of the 1968 World Series.
Wainwright was a 14-game winner coming off reconstructive elbow surgery that sidelined him all of 2011, with 10 of the wins coming at home. He's been a post-season ace with a microscopic 0.77 ERA and 32 strikeouts in 23 1-3 innings.
He fanned Bryce Harper and Ryan Zimmerman twice each and seventh-place hitter Espinosa all three times.
Gonzalez allowed just one hit in five innings, on David Freese's full-count bouncer between third and short to start the fourth. But he had trouble finding catcher Kurt Suzuki's glove.
The second inning was Gonzalez' shakiest when he allowed the Cardinals to score twice and take the lead without a hit. Gonzalez walked four of the first five hitters, putting St. Louis in position to score one run on a wild pitch and a second on Jon Jay's bases-loaded sacrifice fly.
Nationals right fielder Jayson Werth robbed Daniel Descalso of a two-run homer off with a leaping catch to keep it at 2-1 in the sixth. Descalso had a fielding gem of his own in the seventh, ranging far to his left to glove Harper's grounder and then throwing him out by a few steps.
NOTES: The Cardinals went 0 for 8 with runners in scoring position. ... Garcia was 4-2 with a 2.82 ERA in nine starts at home. The lefty has a 2.48 career ERA at Busch. ... Gonzalez also walked seven on June 11, 2011, when he was with Oakland against the White Sox. ... Kozma committed one error in 26 games after taking over as the regular SS in September for injured Rafael Furcal.