George Clooney & Elisabetta Canalis Call It Quits After Two-Year Relationship

George Clooney & Elisabetta Canalis Call It Quits After Two-Year Relationship

George Clooney is back on the market -- the actor has split from his girlfriend, Elisabetta Canalis, after nearly two years of dating.

"We are not together anymore," the former couple said in a joint statement released to Access Hollywood on Wednesday. "It's very difficult and very personal, and we hope everyone can respect our privacy."

PLAY IT NOW: ‘Matchmaker’ Patti Stanger Makes Her Hollywood Couples Predictions

As previously reported on AccessHollywood.com, George, 50, and Elisabetta, 32, began dating in September 2009.

While the cause of the breakup is unknown, Elisabetta recently declared she "will be married someday," despite her now-ex-boyfriend's infamous anti-marriage stance.

VIEW THE PHOTOS: Celebs Who Moved To Splitsville In 2011

"I am a firm believer in marriage -- in the future I will be married," the beauty told Italy's Chi magazine in an interview published earlier this month. "But for the time being, I am happy as I am."

Meanwhile, George has remained steadfast in his commitment to remain single

"I hate to blow your whole news story, but I was married," the actor/philanthropist said in an interview on CNN's "Piers Morgan Tonight" in January, when asked by his father Nick (who appeared alongside the actor) about considering marriage. "Yeah, so I've proven how good I was at it, and I just. ... I'm allowed one."

VIEW THE PHOTOS: The Always Dapper Gentleman George Clooney

George was married to actress Talia Balsam - currently known for her role as Mona Sterling on AMC's "Mad Men" -- from 1989 to 1993, but the union ended in divorce.

Copyright 2011 by NBC Universal, Inc. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

VIEW THE PHOTOS: Ready For Their Close Ups — Models-Turned-Movie Stars!

Related Content from AccessHollywood.com:

VIEW THE PHOTOS: Big Screen Gentlemen: Hollywood’s Leading Men PLAY IT NOW: 2010 Oscars Red Carpet: George Clooney - Jeff Bridges ‘Better Give A Rockin’ Acceptance Speech’… Or Else

More from Access: [ George Clooney Elisabetta Canalis Break-Ups ]