By Gene Emery (Reuters Health) - A large U.S. study designed to gauge the health benefits of vitamin D and fish oil supplements concludes that the omega-3 oil can dramatically reduce the odds of a heart attack while vitamin D's benefits seem to come from lowering the risk of death from cancer. Neither vitamin D nor fish oil lowered the odds of stroke or of getting cancer in the first place in the trial, whose participants did not know whether they were taking the real supplements or a dummy pill. The heart attack rate in fish oil recipients was 28 percent lower than among those who got the dummy pill, or placebo, and it was 77 percent lower among African American participants - although the lead author of the study told Reuters Health that this dramatic drop in risk among black participants needs to be confirmed. For people taking vitamin D who developed cancer, the death rate from cancer was 25 percent lower, possibly because the vitamin "may affect the biology of the tumor so it's less likely to spread and become metastatic," said lead author Dr. JoAnn Manson, chief of the division of preventive medicine at Brigham and Women's Hospital in Boston. "Therefore, you may see a reduction in cancer death but not see a reduction in the first diagnosis, which might take a much longer trial," she said in a telephone interview. "If you're talking about prevention of cancer, that may take treatment for well over a decade." It took a few years of vitamin D use for the reduction in cancer deaths to become clear. The results were reported Saturday at the American Heart Association Scientific Sessions meeting in Chicago and online in the New England Journal of Medicine. Both supplements have a reputation for being beneficial based on animal tests and observational studies involving large diverse populations or ethnic groups. But large studies that directly test the benefits of vitamin D and fish oil in supplement form have given inconsistent results. The new study, known as VITAL, is the first large test of both in the general population. Most previous research has focused on volunteers with an elevated risk of heart attack, stroke and/or cancer. The researchers gave 2,000 international units of vitamin D per day, 1 gram of marine omega-3 fatty acids, or placebo supplements to 25,871 volunteers aged 50 or older. None had a history of cancer, heart attack or stroke. At least half stayed in the study for more than five years. Based on the new findings, "people already taking vitamin D or fish oil will feel there's no reason to stop," Manson said. Others may want to wait "because we are going to be publishing findings for other endpoints - diabetes, cognitive function, depression, autoimmune diseases - over the next six months," she said. "These findings may help people decide if the benefits are likely to outweigh the risks for them." And people should not be taking higher doses than what was used in the study, Manson noted. With megadoses, "the risk may outweigh the benefit. With high doses of vitamin D there can be a risk of high blood calcium levels developing. Some have suggested a higher risk of cardiovascular disease, falls and even fractures." By other measures, neither supplement seemed useful. Among fish oil recipients, the rates of death from any cause, death from cancer and death from heart disease in general were not significantly different than for people not taking fish oil supplements. In addition, the collective odds of having a heart attack, stroke or death from any cardiovascular cause were essentially the same whether people were taking fish oil or placebo. It was only when researchers teased out individual elements of heart disease - such as the rate of heart attack, the rate of fatal heart attack and the need for angioplasty - that a benefit stood out. Even a little fish oil seemed to help. Volunteers who consumed less fish than average - less than one-and-a-half servings per week – and received the real omega-3 supplements saw a 40 percent reduction in the risk of a heart attack. In the vitamin D study, which was "the largest high-dose randomized trial of vitamin D in the world," according to Manson, supplement and non-supplement recipients had similar rates of heart attack, stroke, death from heart attack and cancers of the breast, prostate, or the colon and rectum. It was only the odds of dying from cancer that were reduced. SOURCES: https://bit.ly/2PP7RT2, https://bit.ly/2FcO2Ba and https://bit.ly/2OCRoN3 The New England Journal of Medicine, online November 10, 2018.
Our goal is to create a safe and engaging place for users to connect over interests and passions. In order to improve our community experience, we are temporarily suspending article commenting
- Business Insider
A North Korean man who smuggled 'Squid Game' into the country is to be executed by firing squad and a high-school student who bought a USB drive with the show will be jailed for life, report says
Six other students who watched "Squid Game" were sentenced to hard labor and their teachers may be sent to remote mines, Radio Free Asia reported.
- Spartans Wire
REPORT: Michigan State football could be missing up to 20 players against Penn State
- Miami Herald
A mom in Florida helped her son out in a pinch. Actually, more than a pinch.
Instagrammer Fyza Ali, who is known as a Kylie Jenner look-a-like, asked people to "understand" that she was struggling following her mother's death.
- USA TODAY Sports - Golfweek
Live updates from The Match between Brooks and Bryson.
European champions Italy and Portugal could meet for a place at the 2022 World Cup after being drawn in the same play-off path on Friday.
Princess Victoria, Queen Letizia and more dipped into the royal jewelry vaults for a visit 40 years in the making
The far-right Republican said the Kenosha, Wisconsin, killer was a "hero" who deserves a Congressional Gold Medal.
Jenna Bush Hager's daughter Poppy Louise, 6, tenderly gave her new cousin Cora Georgia, 2 months, a kiss on the cheek in one sweet shot
- Miami Herald
"This bear learned how to close the front door to my house."
- Eat This, Not That!
You pour it out, wear it on your sleeve and love people from the bottom of it. But do you take care—we mean, proper care—of your heart?For decades, heart disease has been the No. 1 killer of Americans.The good news: You can make quick, easy changes to your lifestyle to cut your risk, and add years to your life, and it's never too late. Here are the top 50 things you're probably doing that put you in danger—from the Eat This, Not That! Health to you, with all our heart. Read on—and to ensure your
- Touchdown Wire
The Lions are 0-10-1 after finding another way to screw up a game
- Country Living
Model and actress Elizabeth Hurley, 55, is showing off her toned abs in multiple bikini Instagrams from her "pretend vacation." Here's how she stays so fit:
- Best Life
Whether you're playing football with your friends or participating in an intense trivia night, you might be someone who's always in it to win it. There are also times where a little competition can be good for you. Some people thrive on competition, which helps them perform better both in the workplace and in their personal lives. But while everyone behaves differently in a contest, some competitors are much more ruthless than others. Research conducted by RunRepeat—a review and ranking site tha
- NY Daily News
A GoFundMe page aimed at raising $5 million bail for the Wisconsin man accused of plowing his SUV through a Christmas parade in Waukesha has been pulled from the platform. Darrell Brooks Jr. was charged with five counts of first-degree intentional homicide following the holiday event on Sunday. Five people were pronounced dead on the scene while a sixth victim, 8-year-old Jackson Sparks, died ...
The Mets have agreed to sign infielder Eduardo Escobar to a two-year deal, pending a physical.
No matter what device you’re using, you have to be on the lookout for scams. Any email you receive, text someone sends you, or app you download could be dangerous. We can’t even go a week without a new threat popping up, and the latest crucial warning concerns a collection of fake Android apps on … The post Google just banned 150 dangerous Android apps, so delete them immediately appeared first on BGR.
- LSU Tigers Wire
Whats the buzz according to Dennis Dodd?
Anyone who’s a serious fan of Sonic, or of Macy’s Thanksgiving Day Parade, is probably aware of the 1993 event in which a Sonic the Hedgehog float became caught in high winds, struck a lamppost and injured two people. The thing is, despite knowing this happened, we didn’t have any surviving video of the incident.
A man and a woman were taken to the hospital in critical condition