Enhancing bipolar disorder treatment with vitamin D3 and zinc

Bipolar disorder affects approximately 2.5% of the U.S. adult population and often necessitates a complex treatment approach. Traditional medications such as lithium and olanzapine are commonly used; however, recent research published in Nutritional Neuroscience last month suggests that integrating vitamin D3 and zinc could enhance treatment efficacy and reduce side effects.

Prescription-strength lithium has several potent side effects, including tremors, increased urination and thirst, impaired concentration and stomachaches. It also has the potential to induce hypothyroidism. Olanzapine, on the other hand, can cause drowsiness, weight gain and, in some cases, tardive dyskinesia.

This integration of vitamin D3 and zinc with traditional medications could offer millions of people a more holistic approach to managing the complex condition of bipolar disorder.

Bipolar disorder is characterized by dramatic mood swings, ranging from manic highs to depressive lows. During manic episodes, individuals may experience excessive happiness, irritability, rapid speech and a flood of ideas. This can escalate to risky behaviors and, in severe cases, psychosis. Traditional treatment often involves medications that, while effective, can lead to significant side effects.

Vitamin D3 is crucial for brain health, particularly in mood regulation. People with bipolar disorder are almost always deficient in it. It can help stabilize mood swings that are characteristic of bipolar disorder by controlling pro-inflammatory cytokines and reducing inflammation in the brain.

Similarly, zinc plays a vital role in neurotransmitter function, helping to modulate brain activity and calm manic symptoms. It does this by reducing glutamate while enhancing GABA activity. This dual-pronged effect soothes the brain during manic episodes. It soothes all of us, for that matter!

The use of vitamin D3 and zinc supplements, along with lithium and olanzapine, could potentially allow for lower medication doses, thereby reducing the risk of side effects. This aligns with the growing recognition of the importance of comprehensive treatment strategies that not only reduce symptoms, but also enhance a person’s quality of life.

You should not self-treat. Here’s why. The use of vitamin D3 and zinc should be approached with caution because, if you take too much D3, you could give yourself hypercalcemia. As for zinc, taking excessive amounts — or inferior types — of zinc will just upset your stomach, disrupt immunity and tilt other minerals out of whack.

One must balance minerals and neurotransmitters in the body very carefully; we shouldn’t take stuff and hope for the best, especially when treating bipolar disorder.

It’s important for anyone considering these supplements to consult with a health care practitioner. If he/she approves, then go for it, starting with low doses and just one nutrient at a time.

This brand-new study highlights the potential for nutraceuticals to complement and enhance traditional drug therapy for bipolar disorder.

If you’d like to read more on mental health issues, or another health concern, I invite you to use my search box at suzycohen.com. Also, you’ll find a longer version of this article on bipolar disorder.

This article originally appeared on The Gainesville Sun: Enhancing bipolar disorder treatment with vitamin D3 and zinc