New England Patriots vs. Buffalo Bills picks, predictions: Who wins NFL Week 13 game?

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The New England Patriots and Buffalo Bills play Monday (Dec. 6) in the final game on the NFL Week 13 schedule.

Which team will get the victory?

Check out these NFL Week 13 odds and these NFL Week 13 picks and predictions for the game, which can be seen at 6:15 p.m. MST time on ESPN or ESPN2.

The Bills are a 3.5-point favorite in the game, according to Tipico Sportsbook.

The Bills are -160 on the money line and the Patriots are+130?.

The over/under for the game is set at 44.5 points.

More: New England Patriots vs. Buffalo Bills TV information: How to watch NFL Week 13 game

More NFL Week 13 picks, predictions, odds:

Pro Football Network: Patriots 24, Bills 22

Ben Rolfe writes: "Trying to work out which Bills team will show up in Week 13 is tough to do. They have alternated crushing victories with head-scratching losses in the last five weeks. The pattern says it is time for a devastating loss. However, they did break the curse of Bill Belichick last season with their first victory since 2016, going 2-0 over the Patriots. The Patriots have been superb in the past six weeks, winning by an average of around 25 points per game. This should be a tougher battle against a Bills team coming off extended rest. This should be a close game, and the play here feels like the Patriots to at least cover, if not win."

NFL Week 13 television information:

Sportsnaut: Patriots 27, Bills 24

Matt Johnson writes: "Before the season, this seemed like an unwinnable game for the Patrots. Entering Week 13, the Patriots should be favored. New England can pressure Josh Allen with four pass rushers, can use the right mix of coverages to contain Stefon Diggs and they will run the football effectively. We’re smelling a win."

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Draft Kings: Take the Patriots with the points vs. Bills in Week 13

Teddy Ricketson writes: "This is the first matchup between these AFC East divisional opponents and they play each other twice in December. The Patriots' offense is starting to click under Mac Jones and that is dangerous. This game will be a true test of where they are as the Bills' defense has been solid this year. The Patriots also have a great defense that has been pivotal in their six-game win streak. This should be a fun game to watch, but I think the Pats surprise the Bills in this one and cover the +3.5."

More: NFL playoff picture: NFC, AFC playoff races tighten ahead of NFL Week 13 games

Sports Betting Dime: Patriots vs. Bills game is a coin flip

Chris Amberley writes: "The Pats are third in overall DVOA, and second on defense. This game is a virtual coin flip, and given that home field is worth roughly 3 points, it makes perfect sense for the line to open at up at that number. Don’t expect any movement in either direction this week."

More: NFL Week 13 odds: Point spreads, money lines, over/unders for Week 13 NFL game betting

Will Josh Allen and the Buffalo Bills beat the New England Patriots in NFL Week 13?
Will Josh Allen and the Buffalo Bills beat the New England Patriots in NFL Week 13?

Sportsnaut: Patriots 24, Bills 21

Vincent Frank writes: "This is the ultimate litmus test for the Bills and the stakes couldn’t be more significant. A win over the New England Patriots would trust Buffalo back into the conversation as a Super Bowl contender. But if they lose at home and the Patriots dominate with the rushing attack and defense, the Bills will deserve all the skepticism moving forward."

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FiveThirtyEight.com: Bills have a 56% win probability

The site fives the Patriots a 44% win probability in the NFL Week 13 game.

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ESPN: Bills have a 64.3% chance to win

The site's Football Power Index gives the Patriots a 35.5% chance to pick up the victory in the Week 13 NFL game.

More: NFL Week 13 picks, predictions: Who wins each Week 13 NFL game?

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: New England Patriots vs. Buffalo Bills picks, odds NFL Week 13