Bristol-Myers' RA Drug Orencia Encouraging

Bristol-Myers Squibb Company’s (BMY) rheumatoid arthritis (RA.V) drug Orencia (125 mg) performed well in a phase IIIb study (AVERT: n= 351). The study evaluated Orencia in combination with methotrexate (MTX) as a first-line therapy for adults suffering from the chronic autoimmune disease.

Data from the active-controlled study revealed that at 12 months of treatment, 60.9% patients in the Orencia plus MTX arm achieved DAS-defined (DAS28 CRP
In addition, data from the study revealed that even after the withdrawal of all RA drugs, the benefits were maintained (for 6 months) in more patients in the combination arm than those treated solely with MTX. Orencia was also found to be well tolerated in the study. Bristol-Myers presented the data at the annual meeting of the European League Against Rheumatism (:EULAR).

Orencia, one of the older drugs at Bristol-Myers, is available both in intravenous as well as subcutaneous forms. The drug performed well in the first quarter of 2014, with sales climbing 13% year over year to $363 million.

Besides Bristol-Myers, we note that the RA market includes players like Pfizer (PFE) and AbbVie (ABBV).

Bristol-Myers carries a Zacks Rank #3 (Hold). An example of a better-ranked stock in the healthcare space is Gilead Sciences (GILD), carrying a Zacks Rank #1 (Strong Buy).

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