Tom Holland, who is playing Spider-Man in next year's Spider-Man: Homecoming, is in negotiations to join Daisy Ridley in Lionsgate's post-apocalyptic thriller Chaos Walking.
Doug Liman is directing the project, an adaptation of the best-selling YA novel by Patrick Ness.
The story takes place in a world where all women have been killed by a germ and all living creatures can hear one another's thoughts in a stream of images, words and sounds called Noise.
Holland would star as a boy forced to flee his town with his loyal dog and who comes upon a strange sight: a girl (Ridley).
Oscar-winning screenwriter Charlie Kaufman (Eternal Sunshine of the Spotless Mind) worked on the script, as did Jamie Linden (Money Monster).
Doug Davison, who produced the Liman-directed Tom Cruise starrer Mena, is producing alongside Allison Shearmur (Rogue One, Cinderella).
Holland made his feature debut with the 2012 tsunami drama The Impossible and made a splashy superhero debut as Peter Parker in this year's Captain America: Civil War. Earlier this month, he signed on for a key role opposite Benedict Cumberbatch and Michael Shannon in the period drama The Current War.
Holland is repped by WME.