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Lizzy Caplan in 'Save The Date' (2012)
Caplan bridged the gap between the comedy work she made her name with (“Mean Girls,” “Party Down”), and her more serious, and now Emmy-nominated, turn in Showtime's “Masters Of Sex,” with a lovely performance in this somewhat underrated indie rom-com. Playing a young artist who breaks up with her boyfriend (Geoffrey Arend) when he proposes to her, only to fall into a rebound relationship with marine biologist Mark Webber, Caplan is totally unafraid to appear unsympathetic, even selfish. And yet she’s able to make her character vulnerable and empathetic underneath the steeliness: her sense of twentysomething confusion is palpable. It’s an unusually complex performance for the genre, and maybe serves as the archetypal Caplan performance to date.

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