1. Neve Campbell as Sidney Prescott in Scream : Everett Collection
Neve Campbell as Sidney Prescott in Scream (2022): Paramount Pictures / Courtesy Everett Collection
Neve Campbell today: Appeared in: Scream, Scream 2 , Scream 3 , Scream 4 , and Scream (2022).
Where you know her from: You may recognize Neve from Party of Five, House of Cards , and Clouds.
Kevin Mazur / Getty Images 2. Courteney Cox as Gale Weathers in Scream : Dimension Films / Courtesy Everett Collection
Courteney Cox as Gale Weathers in Scream (2022): Paramount Pictures / Courtesy Everett Collection
Courteney Cox today: Appeared in: Scream, Scream 2, Scream 3, Scream 4, and Scream (2022).
Where you know her from: You may recognize Courteney from Friends, Bedtime Stories, and Cougar Town .
Matt Winkelmeyer / Getty Images for UCLA Institute of the Environment & Sustainability 3. David Arquette as Dewey Riley in Scream : Dimension Films / Courtesy Everett Collection
David Arquette as Dewey Riley in Scream (2022): Paramount Pictures / Courtesy Everett Collection
David Arquette today: Appeared in: Scream, Scream 2, Scream 3, Scream 4, and Scream (2022).
Where you know him from: You may recognize David from Never Been Kissed , Eight Legged Freaks , and Amanda & Jack Go Jumping.
Michael Bezjian / Getty Images for Mash Gallery 4. Skeet Ulrich as Billy Loomis in Scream : Dimension Films
Skeet Ulrich as Billy Loomis in Scream (2022): Skeet Ulrich today: Appeared in: Scream and Scream (2022).
Where you know him from: You may recognize Skeet from The Craft , Jericho, and Riverdale .
Jason Mendez / Getty Images 5. Jamie Kennedy as Randy Meeks in Scream : Dimension Films
Jamie Kennedy as Randy Meeks in Scream 2 : Miramax / Courtesy Everett Collection
Jamie Kennedy today: Appeared in: Scream and Scream 2.
Where you know him from: You may recognize Jamie from Ghost Whisperer, Malibu's Most Wanted, and Son of the Mask.
Frazer Harrison / Getty Images 6. Liev Schreiber as Cotton Weary in Scream : Dimension Films
Liev Schreiber as Cotton Weary in Scream 3 : Dimension Films
Liev Schreiber today: Appeared in: Scream, Scream 2, and Scream 3.
Where you know him from: You may recognize Liev from X-Men Origins: Wolverine, Spotlight, and Ray Donovan .
Slaven Vlasic / Getty Images 7. Matthew Lillard as Stu Macher in Scream : Dimension Films
Matthew Lillard today: Appeared in: Scream.
Where you know him from: You may recognize Matthew from Scooby-Doo, He's All That, and Good Girls .
Kevin Winter / WireImage / Getty Images 8. Drew Barrymore as Casey Becker from Scream : Dimension Films / Courtesy Everett Collection
Drew Barrymore today: Appeared in: Scream .
Where you know her from: You may recognize Drew from 50 First Dates, He's Just Not That Into You, and Santa Clarita Diet .
Jason Mendez / Getty Images 9. Jada Pinkett-Smith as Maureen Evans in Scream 2 : Miramax / Courtesy Everett Collection
Jada Pinkett-Smith today: Appeared in: Scream 2.
Where you know her from: You may recognize Jada from Gotham, The Matrix: Reloaded, and Red Table Talk.
Miikka Skaffari / FilmMagic / Getty Images 10. Omar Epps as Phil Stevens in Scream 2 : Miramax / Courtesy Everett Collection
Omar Epps today: Appeared in: Scream 2.
Where you know him from: You may recognize Omar from House, This Is Us, and Love & Basketball.
Jamie Mccarthy / Getty Images for STARZ 11. Heather Matarazzo as Martha Meeks in Scream 3 : Dimension Films
Heather Matarazzo as Martha Meeks in Scream (2022): Heather Matarazzo today: Appeared in: Scream 3 and Scream (2022).
Where you know them from: You may recognize Heather from Princess Diaries and Saved!
Rodin Eckenroth / Getty Images 12. Scott Foley as Roman Bridger in Scream 3 : Dimension Films
Scott Foley today: Appeared in: Scream 3.
Where you know him from: You may recognize Scott from Scandal, True Blood, and Grey's Anatomy .
Frazer Harrison / Getty Images 13. Parker Posey as Jennifer Jolie in Scream 3 : Dimension Films
Parker Posey today: Appeared in: Scream 3.
Where you know her from: You may recognize Parker from Josie and the Pussycats, Lost in Space, and The Staircase .
Michael Tran / FilmMagic / Getty Images 14. Marley Shelton as Judy Hicks in Scream 4 : Paramount Pictures
Marley Shelton as Judy Hicks in Scream (2022): Paramount Pictures / Courtesy Everett Collection
Marley Shelton today: Appeared in: Scream 4 and Scream (2022).
Where you know her from: You may recognize Marley from Eleventh Hour, Rampage, and Uptown Girls .
Steve Granitz / WireImage / Getty Images 15. Emma Roberts as Jill Roberts in Scream 4 : Dimension Films / Courtesy Everett Collection
Emma Roberts today: Appeared in: Scream 4.
Where you know her from: You may recognize Emma from Scream Queens , Nerve, and Holidate .
Amy Sussman / Getty Images 16. Hayden Panettiere as Kirby Reed in Scream 4 : Dimension Films / Courtesy Everett Collection
Hayden Panettiere today: Appeared in: Scream 4.
Where you know her from: You may recognize Hayden from I Love You, Beth Cooper; Heroes; and Nashville .
Robert Kamau / GC Images / Getty Images 17. Melissa Barrera as Sam Carpenter in Scream (2022): Paramount Pictures / Courtesy Everett Collection
Melissa Barrera today: Appeared in: Scream (2022).
Where you know her from: You may recognize Melissa from In the Heights and Vida .
Jamie Mccarthy / Getty Images for Tribeca Festival 18. Jack Quaid as Richie Kirsch in Scream (2022): Paramount Pictures / Courtesy Everett Collection
Jack Quaid today: Appeared in: Scream (2022).
Where you know him from: You may recognize Jack from The Boys, Plus One, and Logan Lucky .
Phillip Faraone / FilmMagic / Getty Images 19. Jasmin Savoy Brown as Mindy Meeks-Martin in Scream (2022): Paramount Pictures / Courtesy Everett Collection
Jasmin Savoy Brown today: Appeared in: Scream (2022).
Where you know her from: You may recognize Jasmin from For the People, The Leftovers, and Yellowjackets .
Alberto E. Rodriguez / Getty Images 20. Mason Gooding as Chad Meeks-Martin in Scream (2022): Paramount Pictures / Courtesy Everett Collection
Mason Gooding today: Appeared in: Scream (2022).
Where you know him from: You may recognize Mason from Love, Victor; Booksmart; and Let It Snow .
NBCU Photo Bank via Getty Images 21. Dylan Minnette as Wes Hicks in Sceam (2022): Paramount Pictures / Courtesy Everett Collection
Dylan Minnette today: Appeared in: Scream (2022).
Where you know him from: You may recognize Dylan from 13 Reasons Why, Scandal, and The Open House .
Jeff Kravitz / FilmMagic / Getty Images 22. Mikey Madison as Amber Freeman in Scream (2022): Paramount Pictures / Courtesy Everett Collection
Mikey Madison today: Appeared in: Scream (2022).
Where you know her from: You may recognize Mikey from Once Upon a Time...In Hollywood, Better Things, and The Addams Family (2019).
Rodin Eckenroth / FilmMagic / Getty Images 23. And Jenna Ortega as Tara Carpenter in Scream (2022): Paramount Pictures / Courtesy Everett Collection
Jenna Ortega today: Appeared in: Scream (2022).
Where you know her from: You may recognize Jenna from Wednesday, You, and Jane the Virgin .
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