Deadpool, played by Ryan Reynolds, read the rest of Colbert's monologue off the the teleprompter. He joked, "You know, you're not going to believe this, but Donald Trump is in the news. The administration is still dealing with the fallout from Trump announcing that the U.S. will be pulling out of the Iran deal. It's Trump's biggest pulling out blunder since Eric."
Deadpool also brought up one of Colbert's favorite Trump topics, the "pee pee tape." Deadpool joked, "And president Trump spent the day complaining on Twitter about leaks inside the white house, because we all know Trump prefers his leaks in Russian hotel rooms."
Deadpool continued to joke about the subject saying, "You get it, Stephen? Because the president watched two Russian prostitutes urinate on a hotel mattress." But Colbert interjected, "Allegedly." Deadpool realized his error, and said "Right, right, allegedly. Could've been three prostitutes."
Shortly after that joke, Deadpool was killed off in a manner consistent with Avengers: Infinity War villain, Thanos. As Deadpool was succumbing to the infinity stones he mocked Colbert saying, "Thanos? You don't have the budget for this, Colbert."