"Kelly Osbourne is departing E!s 'Fashion Police' to pursue other opportunities, and we would like to thank her for her many contributions to the series over the past five years, during which time the show became a hit with viewers," E! said in a statement.
Then, in March, Kathy Griffin (who joined following the death of Joan Rivers) exited the show saying that her style of comedy didn't "fit with the creative direction."
"Fashion Police" will continue to feature a new celebrity guest each episode, as it had implemented following Osbourne and Griffin's departures.
The show returns on Jan. 11 with Golden Globes coverage.
Also on HuffPost:
Celebrity Photos: December 2016
Lea Michele surprises an Amazon Prime Now customer in LA with a Golden Ticket prize.
Celebrity Photos: December 2016
Anna Camp and Skylar Astin, Amex Blue Cash Everyday ambassadors and newlyweds, prepare for the holidays.
Celebrity Photos: December 2016
Brooke Burke and her kids stocked up on animal pillows from Walmart.
Celebrity Photos: December 2016
Chicago PD star Sophia Bush out holiday shopping.
Celebrity Photos: December 2016
Bethenny Frankel surprises fans purchasing Skinnygirl Market Fresh Deli at a Miami Publix.
Celebrity Photos: December 2016
Bella Hadid makes her DJ debut with friend DJ Nicole Sky at the PAPER Magazine TIDALs party at Gilded Lily in NYC
Celebrity Photos: December 2016
DJ Pauly D got into the holiday spirit as he deejayed during his residency at The Pool After Dark in Harrahs Resort Atlantic City
Celebrity Photos: December 2016
AnnaLynne McCord feeding her cat Temptations food.
Celebrity Photos: December 2016
Eric and Jessie James Decker with Old Navy treating the Madison Square Boys & Girls Club to a PJ party.
Celebrity Photos: December 2016
Tia Mowry using her Chase Freedom card while shopping.
Celebrity Photos: December 2016
Ellie Goulding performs onstage during the Musicians On Call Deck The Halls Holiday Sweater Party at Kola House.
Celebrity Photos: December 2016
Camila Alves for Target.
Celebrity Photos: December 2016
Sophia Bush arriving to the set of Chicago PD.
Celebrity Photos: December 2016
Actor Jeremy Piven on a Zero-G, weightless flight hosted by Pepsi Zero Sugar as part of their #GetZero campaign
Celebrity Photos: December 2016
Curtis 50 Cent Jackson with FRIGO by RevolutionWear at the Bloomingdales King of Prussia
Celebrity Photos: December 2016
Olivia Palermo enjoying Nespresso coffee while holiday shopping at their Soho boutique
Celebrity Photos: December 2016
Madonna hosted a live auction fundraiser and performance on Dec. 3 for her charity Raising Malawi. She toasted and sipped Perrier-Jouët Belle Epoque throughout the star-studded evening at Faena Forum during Art Basel in Miami.
Celebrity Photos: December 2016
Big Sean and Jhene Aiko at the Moschino Takes Miami party during the week of Art Basel with specialty drinks by Tequila Don Julio
Celebrity Photos: December 2016
Russell Simmonsand Jeremy Scott at the Moschino Takes Miami party where guests enjoyed specialty drinks by Tequila Don Julio
Celebrity Photos: December 2016
Cate Blanchett in her Giorgio Armani Si campaign
Celebrity Photos: December 2016
Olivia Culpo leaving her hotel wearing the Pepsi Holiday Emoji sweatshirt while hailing a taxi in NYC
Celebrity Photos: December 2016
Alison Sweeney gets into the holiday spirit by stuffing her family's stockings with an Arm & Hammer Spinbrush and goodies.
Celebrity Photos: December 2016
Reese Witherspoon holiday shopping at Tiffany & Co Beverly Hills.
Celebrity Photos: December 2016
Ice-T gets Matchy-Matchy with his bulldog Maximus as part of Cesar® Brand’s holiday campaign.
Celebrity Photos: December 2016
Kristin Chenoweth posted a photo of her enjoying Trop50 backstage at Hairspray Live! in LA
Celebrity Photos: December 2016
Coco Austin and Ice-T celebrated their daughter Chanels 1st birthday party at Sugar Factory American Brasserie in NYC
Celebrity Photos: November 2016
Jamie Chung celebrates in style with savory treats and her DIY Smithfield Bacon Bar.
Celebrity Photos: November 2016
Actress Ashley Benson joined PayPal on #GivingTuesday to encourage online donations to thousands of worthy causes
Celebrity Photos: November 2016
Katie Holmes leaving NYC restaurant Kola House.
Celebrity Photos: November 2016
Alysia Reiner hosted Cool Effect's #SaveOurSnowmen climate change mockumentary screening alongside Snowmen protestors in NYC on Giving Tuesday.
Celebrity Photos: November 2016
Margot Robbie face of deep euphoria Calvin Klein attends the IFP Gotham Independent Film Awards which were sponsored by the fragrance
Celebrity Photos: November 2016
Cate Blanchett and Amy Adams attend the deep euphoria Calvin Klein sponsored IFP Gotham Independent Film Awards.
Celebrity Photos: November 2016
Whitney Port picks up holiday gifts at the new Marshalls store in Brooklyn.
Celebrity Photos: November 2016
Katie Holmes out and about wearing the new Thursday Boot women's collection.
Celebrity Photos: November 2016
Olivia Culpo looking stylish in Rampage boots in LA.
Jason Fitz and Frank Schwab join forces to recap the draft in the best way they know how: letter grades! Fitz and Frank discuss all 32 teams division by division as they give a snapshot of how fans should be feeling heading into the 2024 season. The duo have key debates on the Dallas Cowboys, New York Giants, New Orleans Saints, Los Angeles Rams, New England Patriots, Las Vegas Raiders and more.
The first electric vehicle I ever drove was a Tesla Roadster in 2011. It was with great anticipation that I slid behind the wheel of the 2025 Acura ZDX Type S. Sure, it's a midsize SUV, but it wears the Type S moniker, a name reserved only for the most fun-to-drive in the Acura stable. On launch, the ZDX will be available in A-Spec and Type S trims -- both of which come equipped with a 102 kWh battery.
The NFL will allow players to wear protective Guardian Caps during games beginning with the 2024 season. The caps were previously mandated for practices.
