Cure for Obesity: Freeze-Dried Poop?
Dr. Thomas Louie, an infectious disease specialist at the University of Calgary, holds a container of stool pills. (Image via AP Photo/The Canadian Press, Jeff McIntosh)
Atkins, paleo, juice cleanses … people will try most anything to shed some pounds. How about freeze-dried poop? A clinical trial set to start this year will involve 20 obese patients taking capsules filled with freeze-dried stool from healthy donors to test researchers’ hunch that intestinal microbes can influence people’s weight, Ars Technica reports.
Related: Women Have Overtaken Men in the Obese Category
“We have no idea what the result will be,” lead researcher Elaine Yu admits. However, researchers do have some anecdotal support for the idea that introducing healthy new gut microbes into a person can affect weight. In one study cited by Ars, researchers took gut microbes from a set of twins and put them into some mice. One of the twins was lean, the other was obese. Mice that received microbes from the obese twin got chubby.
Related: Is This the Best Diet for Weight Loss?
Restoring the balance of gut microbes via fecal transplant has been used to treat intestinal Clostridium difficile infections, the New York Times reports. In one case, per Ars, a woman received a fecal matter transplant from her healthy-yet-overweight daughter. The woman’s infection was cured, but she began to gain weight.
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One challenge for the whole enterprise has been creating a suitable capsule to get the job done, the Times notes. Capsules typically dissolve in feces, so when they contain feces, they dissolve from the inside out. A nonprofit called OpenBiome, however, developed a capsule that stays solid at room temperature, then dissolves in the small intestine. The Times notes that researchers are studying the use of poop to treat other maladies as well, such as Crohn’s disease. “Without capsules,“ one doctor says, "we wouldn’t be able to do this kind of work.” (Speaking of fecal matter, it’s in your ground beef.)
By Luke Roney
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This article originally appeared on Newser: Cure for Obesity: Freeze-Dried Poop?
