Tuesday on "The Talk" hosts Sharon Osbourne and Marie Osmond get candid about motherhood and sometimes missing important signs. "My son [Jack] was complaining for months that he had a leg that he couldn't feel, except extreme heat. He said his leg was burning," recalls Osbourne. "I thought oh my God, I hope it's not anything more serious, because this is just going on way too long. I had looked up some of the symptoms that you get for MS... I just had this feeling, and then when he was actually confirmed that he did have MS, my gut kind of already knew it." Osmond, "I feel like I failed as a mother, like with my son who passed away and had depression, I didn't see that. But I have a daughter, it's kind of sad, she came home drunk, and I had no idea. She was just being so sweet and just downloading and talking. Until the next day, I went to the car and found the bottles. I think as mothers you don't want to see it, but you feel like a failure. But I believe we just miss things."