Jennifer Aniston was the final guest on the talk show, which is ending after 19 seasons — and two years after allegations tarnished the host's image.
"This is the truth: There will never, ever be a time like this," Winfrey told her friend, neighbor and mentee DeGeneres. "There will be other great things. But there will never be a time like this. Know that these are the glory days."
Oprah Winfrey made the revelation while discussing her new documentary The Color of Care, which focuses on racial inequities in the healthcare system
Four members of the "Ellen" creative team look back at the show's groundbreaking coming out episode on its 25th anniversary.
It was all part of Global Citizen's Stand Up for Ukraine social media rally.
A federal judge dismissed the lawsuit filed by four sisters of disgraced "19 Kids and Counting" star Josh Duggar over the release of police records in his molestation investigation in the mid-2000s.
"It just sounded so far-fetched," Gayle King says of the iconic car giveaway on PEOPLE's debut episode of Pop Cultured
"It's up to the residents of Pennsylvania to decide who will represent them," the media mogul says in a statement.
Rogen and his wife did not know it was televised and got very high before realizing they were in seats 1a and 1b. He also has never met Adele and had no idea why he was invited.
The superstar, 39, said Tuesday on Instagram that she will "set things square" in an Oprah Winfrey interview one day, but answered the burning question from fans — and the world — about what is is next for her now that #FreeBritney has become #FreedBritney.
The singer tells Oprah Winfrey that "it’s not my job to validate how people feel about their bodies."
Adele spoke to Oprah Winfrey about finding love with sports agent Rich Paul after her split from husband Simon Konecki.
Oprah and Adele talked about the singer's new album, '30,' and life — divorce, single-parenting and falling in love again.
In a new teaser for her 'elegant' and 'filthy' TV special, Adele tells Oprah Winfrey about her Griffith Observatory concert attended by Lizzo and Tyler Perry.
In a new interview with Oprah Winfrey to promote his book, "Will," the actor dealt with questions about his nontraditional marriage.
Markle, who is estranged from his daughter, admits leaving Winfrey a letter at her home in a new interview.
Social media was divided on whether the royal couple were shading the talk show queen or being humorous.
While criticism of Prince Harry is being flung fast and furiously, it's not going to silence him — nor should it, says Oprah Winfrey.
Acclaimed actor's directing debut is love letter to the films of his youth, but with a much more diverse point of view.
The Umbrella Academy star spoke with Oprah Winfrey, on AppleTV+'s The Oprah Conversation, in his first TV interview since coming out as transgender.
Morgan claims Markle was making stuff up in her interview with Oprah Winfrey, even going so far as to compare the duchess to former President Donald Trump.
The Prince of Monaco was asked for his reaction to the explosive March 7 tell-all interview.
Entertainment Tonight reports a source close to the reclusive pop star claims she's considering telling her own story — perhaps to Oprah Winfrey.