Stocks weak as volatile month comes to a close

The Dow and S&P are poised to break a ten-month winning streak. Plus, Spotify is one step closer to being public. And we’ve got big earnings from Salesforce.com and Victoria’s Secret parent L-Brands coming up. Plus, this company is disrupting health care with an Uber-like model. We talk to the CEO of New York startup Maven. Catch The Final Round at 3:55 ET p.m. with Jen Rogers, Yahoo Finance markets correspondent Myles Udland, and Yahoo Finance Editor-in-Chief Andy Serwer.

Winners and losers

Stocks in the red include Celgene as the FDA rejected a drug application for the drugmaker’s experimental MS drug, claiming it was ‘insufficient;’ Hertz as the car rental operator posted a much wider loss than was expected; and Lowe’s, with shares dropping as the home improvement chain missed on earnings, with analysts concerned profit margins are getting squeezed, as rival Home Depot grows faster.

Stocks in the green include Snap as TechCrunch reports that despite backlash about the new app, downloads are up; Etsy as the craft marketplace beat on profit and revenue; and United Technologies, with shares climbing on reports Bill Ackman’s Pershing Capital is building a stake in the industrial manufacturer.