One fan called in and asked MacFarlane, “Has there ever been a celebrity on one of your shows that you parodied and they did not take it so well?”
Macfarlane revealed that Adrien Brody was not very pleased about a bit they did on Family Guy. The bit had an audience watching Brody do sit-ups in a film, but because it was in 3D, it appeared as if a giant nose was attacking them.
Apparently Brody did not appreciate the joke. MacFarlane went up to him a party long after the fact and he explained, “I said, like, ‘Hey, I really liked ‘Splice.’ I hope there’s no hard feelings.” And essentially the upshot was, well, there are. There are some hard feelings.”
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