Seth MacFarlane calls Fox 'Dr. Jekyll and Mr. Hyde' while revealing new 'Family Guy' vaccine PSA

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Seth MacFarlane joined Jimmy Kimmel Live Monday, where he revealed the new Family Guy vaccination PSA. In it, Stewie and Brian address Peter’s vaccine hesitancy, taking on common excuses people give for not getting vaccinated, then providing fact-based information dispelling those misconceptions.

Acknowledging the dichotomy between the information given by his characters from Family Guy, a Fox property, and vaccine conspiracies pushed by some at Fox News, MacFarlane compared Fox to Dr. Jekyll and Mr. Hyde. He went on to speak about how he views the news side of Fox compared to the entertainment side.

“You see on the news side, they obviously are in, you know, their imaginary fairyland,” MacFarlane said. “And then you have the entertainment side that’s like, ‘Alright, we gotta exist with these people, so let's be political and let’s make the best of it.’”

Video Transcript

- Peter might ask is, what if the vaccine makes him sick?

- The common side effects from the COVID vaccines are generally mild and last a few days. But do you know what can have serious long-term side effects? COVID.

KYLIE MAR: "Family Guy" creator, Seth MacFarlane, joined "Jimmy Kimmel Live" Monday, where he premiered a new "Family Guy" vaccination PSA in which Stewie and Brian discuss Peter's vaccine hesitancy.

- And he also says he just figures everyone else is going to get it. So why does he have to?

- Well, what he should understand is that getting the shot not only protects him but also the people around him. But even more importantly, if the virus is allowed to spread through an unvaccinated population, it could mutate into a variant that the vaccines might not protect against.

KYLIE MAR: Kimmel was shocked to learn that the same parent company that allows Fox News hosts to spread crazy conspiracy theories about the vaccine, is the same company that okayed the PSA.

JIMMY KIMMEL: You go to Fox and you tell them you want to do this and then, they're for it?

SETH MACFARLANE: Yeah. It's very sybil of them.

JIMMY KIMMEL: Uh huh. It is.

SETH MACFARLANE: I don't quite know what the-- look, I mean, it's two halves of the same person. It's Dr. Jekyll and Mr Hyde.

KYLIE MAR: MacFarlane also spoke about how he views the dichotomy between the new side at Fox and the entertainment side.

SETH MACFARLANE: You see on the news side, they obviously are in, you know, their imaginary fairyland. And then, you have the entertainment side, it's like, all right, we got to exist with these people so let's be political and let's make the best of it.

KYLIE MAR: And MacFarlane joked about why he felt the need to make the PSA.

SETH MACFARLANE: I looked around and I saw everyone else at Fox corp doing their part to get good science out there and--

[AUDIENCE LAUGHING]

--be responsible with their platforms. And looking down the barrel of that kind of peer pressure, I said, well, gosh, we got to do something too.