Dr. Drew Pinsky is responding to Leah Messer's tough news.
The 23-year-old former Teen Mom 2 star, who left rehab in June, has lost primary custody of her 5-year-old twin daughters, Ali and Aleeah, according to InTouch magazine.
Dr. Drew, who has moderated several Teen Mom reunion shows, said backstage during Thursday's Rachael Ray that while he hasn't been in contact with Messer, when the two last spoke, he was "expecting progress" based on their last interaction at the Teen Mom 2 reunion special.
"If you saw the last reunion show, which is the last time I had contact with her, I believed she was making some progress," Dr. Drew said.
"One of the signs I noticed was that the people around her -- like her ex-husband and his new wife -- were starting to really come down on her," he explained. "When that starts to happen, that's a sign to me that the identified patient is getting better."
"I don't know if this recent issue with the child custody is going to set her back, but I certainly wish her the best," the TV doctor added. "She is working very hard and this has been a terribly painful and stressful time for her. So, let's all wish her the best."
The twins' father, Corey Simms, first fought for custody in 2014, which Messer won when she completed a negative drug test. However, in the couple's most recent battle, school records reportedly showed that the two children had often been late to school, prompting a change in custody.
Some believe that Messer's other ex-husband, Jeremy Calvert, might now seek custody of Messer's child with him, 2-year-old Addie.
Meanwhile, another Teen Mom 2 star, Jenelle Evans, made headlines in August when she broke off her engagement to Nathan Griffin. The 23-year-old revealed to ET that she had given him back the ring.
"I'm enjoying being a mom," Evans said at the time. "I just celebrated my first son's 6th birthday this weekend and it went fantastic. I am not looking to date anyone at the moment. I am focusing on myself."
Later in August, Evans was arrested in Myrtle Beach, South Carolina, and charged with assault after allegedly hitting her ex-fiancé's new girlfriend in the head with a glass.
Evans' rep told ET the incident was a "set up."
"Nathan provoked Jenelle to make her look bad by bringing his new girlfriend to Jenelle's house," her rep claimed. "Jenelle is a positive, focused mother. All she wants is the best for her son and to feel safe around her family and friends."