Patricia Arquette To Be Honored at 28th Annual GLAAD Media Awards in Los Angeles

Patricia Arquette will be honored at the 28th Annual GLAAD Media Awards next month.

The 48-year-old actress will receive the organization's Vanguard Award for her work as a longtime ally and supporter of the LGBTQ community at the Los Angeles awards ceremony at the Beverly Hilton on April 1.

RELATED: 'Moonlight,' 'Transparent' and 'I Am Cait' Among GLAAD Media Award Nominees -- See the Full List

"Patricia Arquette embodies the critical voice needed during these times to resist against injustice and discrimination across a range of issues," GLAAD President & CEO Sarah Kate Ellis said in a press release. "She is a beacon of light who has consistently used her platform to advance equality across marginalized groups and to drive culture-changing conversations that move acceptance forward."

Arquette will also honor her late sister, Alexis Arquette, at the event, remembering the transgender actress' contributions to both film and the LGBTQ community.

Cameron Esposito is set to host the event, with special appearances by Josh Hutcherson, Victoria Justice, Trace Lysette, and Tatiana Maslany, while Jussie Smollett will lead a tribute to Orlando's LGBTQ community with a special performance by Cynthia Ervio.

Only ET will be backstage at the Los Angeles awards ceremony with Arquette, Hutcherson, Smollett and many more celebrities. The event will honor film, television and media in 21 English-language categories and 11 Spanish-language categories. GLAAD will be holding a second ceremony in New York City on May 6.

RELATED: 13 LGBT Reality Series That Changed Queer Life

Robert De Niro was honored at last year's GLAAD Media Awards, and adorably thanked Jennifer Lawrence. See more in the video below.

Related Articles