"I had my scan," an emotional Kris explains, with boyfriend Corey Gamble at her side. "They found a cyst and like a little tumor."
Though the trailer doesn't reveal any further information—such as where the tumor is or whether it's malignant—the clip does show some of the family's reactions. Khloe Kardashian can be seen looking somber, across from Kris, and a subsequent scene shows Kendall providing a comforting hug to Kylie as the beauty mogul dissolves into tears.
But Kris' health isn't the only family member's to take center stage in the oncoming season Kourtney Kardashian's pregnancy with her andTravis Barker's son Rocky, now six months, including the events leading up to and after she underwent fetal surgery.
And of course, the trailer promises lots of interpersonal drama, especially between Khloe and Kim Kardashian.
When Kris asks Kim whether she's talked to her younger sister about an unnamed topic, Kim responds, "No, she's just very judgmental now that Tristan [Thompson] is gone."
Later, after Khloe says during a confessional, "Sisters can be vicious and brutal," the SKIMS founder can be heard saying, "Khloe is unbearable these days."
However, Khloe offers a different take on the ongoing tension, as she tells Kim later on, "You are going through a lot right now and you're taking it out on me."
But where there is drama, there is also fun.
Case in point, the trailer's opening scene where Kendall tells the camera, "Kylie just made me wait an hour for her to do a photoshoot."
"Whatever!" Kylie jokes as she enters the car, before excitedly exclaiming, "It's fashion week!"
Alas, fans will have to wait until May 23 to see all the highs and lows unfold on season five of The Kardashians.
In the meantime, keep reading to see when more of your favorite shows will premiere in 2024.
Love Undercover (Peacock) - May 9
Sins of the South (Oxygen) - May 12
Bridgerton (Netflix) - May 16
Don't Forget the Lyrics (Fox) - May 16
I Can See Your Voice (Fox) - May 16
Race to Survive New Zealand (USA) - May 20
Weakest Link (NBC) - May 20
Gordon Ramsey's Food Stars (Fox) - May 22
The Kardashians (Hulu) - May 23
Gaga Chromatica Ball (HBO) - May 25
Beat Shazam (Fox) - May 28
America's Got Talent (NBC) - May 28
Masterchef (Fox) - May 29
Teen Mom: The Next Chapter (MTV) - May 30
We Are Lady Parts (Peacock) - May 30
We Are Lady Parts (Peacock) - May 30
Clipped (Hulu) - June 4
The Bear (FX & Hulu) - June
The Real Housewives of Dubai (Bravo) - June 2
Gypsy Rose: Life After Lock Up (Lifetime) - June 3
Name That Tune (Fox) - June 3
Becoming Karl Lagerfeld (Hulu) - June 7
Perfect Match (Netflix) - June 7
The Boys (Prime) - June 13
For the latest breaking news updates, click here to download the E! News App
Seven coaches have been hit with the dreaded tag since the 2018 season and the idea of coaches getting canned after one season is not as rare as it used to be.
In the NFL it feels like at least one-third of the league's head coaches are always feeling the heat any given season. Some may even be dead men walking. ESPN and Omaha productions' Kevin Clark joins Charles McDonald on the latest episode of The Exempt List to identify the coaches that are on the hot seat and maybe even 'pre-fired' heading into the 2024 season.
Grays of various shades — white, black and gray itself — are dominant in the automotive colors landscape, while cars that are deemed “colorful” — blues and reds, golds and browns — continue to plummet in popularity, according to a recent data analysis by ISeeCars.com.