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Cuoco, who was nominated for best actress in a comedy series, joked about her loss to "Schitt's Creek" star Catherine O'Hara on Sunday with a video of her celebrating with booze and a "Schitt's Creek" binge.
"OK, SAG Awards are over. Now, I'm going to get back to my favorite show," Cuoco, still wearing her hot pink Prabal Gurung gown, said while crawling into bed and turning on "Schitt's Creek."
"Goodnight and thank you @sagawards ! Wow am I grateful to be a freakin actor. Now to continue binging my favorite show," she captioned the Instagram post.
Cuoco was nominated for her performance in HBO Max's "The Flight Attendant." Other nominees in the category included "Dead to Me" stars Christina Applegate and Linda Cardellini and O'Hara's "Schitt's Creek" co-star Annie Murphy.
This isn't the first time she used humor to cope with an awards show loss. Last month, Cuoco commemorated her Golden Globes defeat with a photo of herself indulging in pizza, cake and champagne while rocking a tiara.
"I would like to thank...never mind !!" Cuoco wrote after losing to O'Hara for best actress in a TV series, musical or comedy.
Known for her role as Penny in the hit sitcom "The Big Bang Theory," Cuoco showed off her comedic and dramatic chops in HBO Max's limited series "The Flight Attendant," which USA TODAY's TV critic Kelly Lawler described as "a melodrama that mixes dark comedy, murder mystery and an emotional story about addiction."
"This is definitely my coming-out party in the sense of showing everyone I can do something other than comedy. It gets quite dark, quite emotional," she told USA TODAY in November. "This is my way of pushing the door down and going, 'I can do more and I love doing more.' "
Steven Molaro, executive producer of "Big Bang" and spinoff "Young Sheldon,"said he was "blown away" by Cuoco's transition after watching the first two episodes of "Flight Attendant."
"It doesn't feel like you're watching Penny. She's a different person," he told USA TODAY. "Between making incredible choices as an actor and being in the moment at the same time, I've never seen anything quite like it."
Contributing: Kelly Lawler, Bill Keveney
This article originally appeared on USA TODAY: Kaley Cuoco jokes about SAG Awards loss by watching 'Schitt's Creek'