In an interview with Access Live on Monday, Cryer, who stars in The CW’s Supergirl, was asked about his experience on the CBS sitcom, which originally centered on Cryer and Sheen as brothers Alan and Charlie, respectively.
In January 2011, the show went on hiatus when Sheen entered rehab. Shortly afterwards, Sheen was infamously fired after a public meltdown that included insulting creator Chuck Lorre. The next season, Sheen’s character was killed off and replaced by Ashton Kutcher, who played a billionaire businessman who buys Charlie’s house after his death until the show concluded in 2015.
Cryer, 53, said while there was “great camaraderie” on set, there was also some chaos.
“It was crazy. It was way more craziness than I really was hoping for, honestly,” he said with a laugh.
“It was tough to watch a guy who I had seen… you know, when we started the show, Charlie had been sober for a while and was really in control of his life,” Cryer continued. “And it was tough to see that go away. That was the hardest part of being involved in that process. But actually doing the shows was always great. There was never a time when it wasn’t great.”
Cryer also revealed that he hasn’t spoken to Sheen, 53, “in a couple of years.”
“It’s kind of a roller coaster when you have Charlie in your life and I just haven’t decided to get back on that roller coaster,” he said.
Sheen, who revealed his HIV-positive diagnosis in 2015, has remained relatively under the radar in recent years.
Last December, he celebrated one year of sobriety.
“I’ve been sober almost 14 months. That was the biggest change for me,” he told PEOPLE in January. “I really focus on my health, my family and work will come next. I’m excited to be excited again.”
Sheen said getting clean hasn’t been a struggle and that he was ready for his life to change.
“I came to it on my own,” he said. “It was just one of those epiphany moments.”