Browns vs. Bengals: Start Corey Coleman, who saw a team-high 11 targets last week, immediately acting as Cleveland’s No. 1 wideout in his first action since Week 2. With Josh Gordon out one more game, Coleman should be heavily involved Sunday.
Start Tyler Kroft, who remains underpriced in DFS despite a matchup against the Browns, who’ve allowed the third-most fantasy points to tight ends.
Bears vs. Eagles: Start Tarik Cohen if you’re desperate in deeper leagues, as he reentered the team’s game plan last week and should be on the field plenty this week with Chicago as 13.5-point dogs.
Start the Eagles defense, as they’ve recorded the second-most interceptions (14) this season, and Mitch Trubisky could be forced to throw more than usual with Philly huge favorites at home.
Dolphins vs. Patriots: Sit Damien Williams and Kenyan Drake, who are in a committee running behind a poor offensive line and up against a New England defense playing extremely well of late.
Start Dion Lewis, who dominated snaps after Rex Burkhead fumbled last week, and the Patriots have the highest implied total (31.75 points) of the week. Lewis should be treated as a top-10 RB in Week 12.
Bills vs. Chiefs: Start Zay Jones, who’s shown signs of life of late, and Kelvin Benjamin is likely to miss Sunday’s game. Jones should be mostly matched up with the burnable Phillip Gaines, so the matchup is right for a breakout performance from the rookie.
Start Alex Smith, who’s coming off a disappointing performance in which the Chiefs failed to score a touchdown coming off a bye over nearly five quarters against a reeling Giants defense. But Kansas City returns home and gets another struggling D, as Buffalo has allowed 45.0 points over the team’s three-game losing streak. Smith, Kareem Hunt and Tyreek Hill are all in store for big bounce back games.
Buccaneers vs. Falcons: Sit Doug Martin, who’s gotten 2.1 YPC over the past three games and just 0.47 fantasy points per opportunity this season, which ranks No. 112 in the NFL.
Start Mohamed Sanu, who has three touchdowns over the past four games and is up against a Tampa Bay secondary that’s allowed the most yards per game (70.2) to No. 2 wide receivers this season…Also, treat Tevin Coleman as a top-five RB this week.
Panthers vs. Jets: Start Devin Funchess, who started to thrive as the team’s new No. 1 WR before their bye. Greg Olsen is back, but Curtis Samuel is out, and the Jets have yielded 20 passing TDs.
Sit Bilal Powell, who can’t be counted on for more than a dozen touches with or without Matt Forte in the lineup. Carolina has the No. 3 ranked Run Defense DVOA.
Titans vs. Colts: Start Corey Davis, who’s seen 17 targets over the last two games and gets a Colts defense that’s allowed an NFL-high 8.3 YPA. This could mark the last time Davis is cheaper in DFS than teammate Rishard Matthews, who’s questionable to suit up for this game.
Start T.Y. Hilton, who’s been the biggest boom or bust fantasy player so far this season, averaging 168.3 yards (with three touchdowns) in three games and 31.4 yards (with no scores) over the other seven contests. The Titans are an inviting matchup for another “boom” in Week 12…Jacoby Brissett is another sneaky cheap play this week, as he’s gotten 7.8 YPA and rushed for three scores over five home games this season.
Seahawks vs. 49ers: Start J.D. McKissic. No one can run for the Seahawks, but McKissic has nine catches over the past two games and faces a Niners defense that’s ceded an NFL-high 617 receiving yards (and four TDs) to running backs.
Sit all 49ers other than Carlos Hyde, as the Seahawks defense should have its way even if depleted, possibly leading to an SF quarterback change at halftime.
Saints vs. Rams: Start Drew Brees, who showed he’s still plenty capable of putting up big numbers if need be during last week’s late comeback. The Over/Under in this game (53.5 points) is by far the highest of the week.
Start Cooper Kupp, who lines up mostly in the slot where New Orleans is most vulnerable. Kupp should approach double digit targets in a projected shootout with Robert Woods sidelined, so he’s a highly intriguing start in Week 12. The Saints defense is improved, but they just lost Alex Okafor for the season, and Marshon Lattimore is highly questionable to play Sunday. Sammy Watkins is another enticing flier with upside this week.
Jaguars vs. Cardinals: Sit Marqise Lee, who’s slated with the tough task of being shadowed by Patrick Peterson. The Jaguars defense should dominate, so this game script screams to fade Lee this week, making Dede Westbrook an interesting “punt” WR option in DFS.
Sit Adrian Peterson. The volume has been nice, but Arizona continues to struggle run blocking, and Jacksonville’s rush defense has greatly improved since trading for Marcel Dareus.
Broncos vs. Raiders: Start Devontae Booker, who saw a season-high 48 snaps last week compared to C.J. Anderson’s 29 (CJA also lost a fumble). Booker is cheap in DFS, and the Raiders sport the last ranked Defense DVOA.
Start Jared Cook. While teammates Amari Cooper and Michael Crabtree will be facing top corners, Cook gets a Broncos defense that’s allowed the second-most fantasy points to tight ends. Cook is quietly on pace to finish with 856 receiving yards this season.
Packers vs. Steelers: Sit all Packers, who have the lowest implied total (14.25 points) of the week. Jordy Nelson has fallen well below Davante Adams with Brett Hundley under center.
Start Martavis Bryant, who’s looking at increased looks with JuJu Smith-Schuster out and should be matched up plenty with the struggling Damarious Randall. And don’t fade Le’Veon Bell in this DFS spot. He’s going to have his best game of the season Sunday night.
Texans vs. Ravens: Sit Lamar Miller, who should act as Houston’s workhorse with D’Onta Foreman out, but the Ravens have a tough D, and Tom Savage continues to destroy the Texans’ offense. DeAndre Hopkins gets a brutal matchup for the second straight week.
Start Danny Woodhead, who saw six targets while playing just 13 snaps during his return last week. Woodhead should see more work Monday night, and with few alternatives on Baltimore’s offense and facing a beat-up Texans defense, Woodhead is a sneaky play in Week 12.