'College GameDay' at Clemson-NC State and our other predictions for ACC football Week 5

The Week 5 ACC football slate has a matchup so solid that ESPN's College GameDay will be there.

Lee Corso and company will set up shop in Death Valley (or Littlejohn Coliseum, depending on how Hurricane Ian develops) as 10th-ranked NC State (4-0, 0-0) travels to face No. 5 Clemson (4-0, 2-0) on Saturday (7:30 p.m., ABC).

One brave expert has picked the Pack to get the upset coming off last season's double-overtime win in Raleigh, but the biggest prediction splits this week come from matchups between Duke and Virginia, and Wake and FSU.

We'll see how it all shakes out Saturday.

Here are our panel members' predictions for all of this week's games including ACC football teams.

HUGE OPPORTUNITY: NC State football vs. Clemson is most important game of Dave Doeren's tenure

RETURNING TIGERS:Clemson football depth chart for NC State shows defensive backs returning to action

HURRICANE PLANNING:Florida State says it can host game as Hurricane Ian looms. Wake Forest coach is less sure

Saturday

Louisville at Boston College (noon, ACC Network)

The picks: Louisville 7, BC 0

  • Sammy Batten, Fayetteville Observer: Louisville

  • Carter Karels, Tallahassee Democrat: Louisville

  • Alexis Cubit, Louisville Courier Journal: Louisville

  • Jim Rice, Greenville News: Louisville

  • David Thompson, Fayetteville Observer: Louisville

  • Scott Keepfer, Greenville News: Louisville

  • Todd Shanesy, Greenville News: Louisville

PLAYERS TO WATCH:6 players to watch as Louisville football looks for first ACC win against Boston College

Virginia Tech at UNC (3:30 p.m., ACC Network)

The picks: UNC 7, Va Tech 0

  • Sammy Batten, Fayetteville Observer: UNC

  • Carter Karels, Tallahassee Democrat: UNC

  • Alexis Cubit, Louisville Courier Journal: UNC

  • Jim Rice, Greenville News: UNC

  • David Thompson, Fayetteville Observer: UNC

  • Scott Keepfer, Greenville News: UNC

  • Todd Shanesy, Greenville News: UNC

No. 21 Wake Forest at No. 22 Florida State (3:30 p.m., ABC)

The picks: Florida State 5, Wake Forest 2

  • Sammy Batten, Fayetteville Observer: Wake Forest

  • Carter Karels, Tallahassee Democrat: Florida State

  • Alexis Cubit, Louisville Courier Journal: Florida State

  • Jim Rice, Greenville News: Florida State

  • David Thompson, Fayetteville Observer: Wake Forest

  • Scott Keepfer, Greenville News: Florida State

  • Todd Shanesy, Greenville News: Florida State

EXPLOSIVE OFFENSE:Wake Forest QB Sam Hartman brings experience and comfortability vs. Florida State

Wagner at No. 25 Syracuse (5 p.m., ACCNX, ESPN+)

The picks: Syracuse 7, Wagner 0

  • Sammy Batten, Fayetteville Observer: Syracuse

  • Carter Karels, Tallahassee Democrat: Syracuse

  • Alexis Cubit, Louisville Courier Journal: Syracuse

  • Jim Rice, Greenville News: Syracuse

  • David Thompson, Fayetteville Observer: Syracuse

  • Scott Keepfer, Greenville News: Syracuse

  • Todd Shanesy, Greenville News: Syracuse

Virginia at Duke (7:30 p.m., RSN/ESPN3)

The picks: Duke 4, Virginia 3

  • Sammy Batten, Fayetteville Observer: Duke

  • Carter Karels, Tallahassee Democrat: Duke

  • Alexis Cubit, Louisville Courier Journal: Virginia

  • Jim Rice, Greenville News: Duke

  • David Thompson, Fayetteville Observer: Virginia

  • Scott Keepfer, Greenville News: Duke

  • Todd Shanesy, Greenville News: Virginia

No. 10 NC State at No. 5 Clemson (7:30 p.m., ABC)

The picks: Clemson 6, NC State 1

  • Sammy Batten, Fayetteville Observer: Clemson

  • Carter Karels, Tallahassee Democrat: Clemson

  • Alexis Cubit, Louisville Courier Journal: Clemson

  • Jim Rice, Greenville News: NC State

  • David Thompson, Fayetteville Observer: Clemson

  • Scott Keepfer, Greenville News: Clemson

  • Todd Shanesy, Greenville News: Clemson

FOR SUBSCRIBERS:Welcome to Clemson week, which holds the key to NC State football's biggest dreams

Georgia Tech at No. 24 Pitt (8 p.m., ACC Network)

The picks: Pitt 7, Ga Tech 0

  • Sammy Batten, Fayetteville Observer: Pitt

  • Carter Karels, Tallahassee Democrat: Pitt

  • Alexis Cubit, Louisville Courier Journal: Pitt

  • Jim Rice, Greenville News: Pitt

  • David Thompson, Fayetteville Observer: Pitt

  • Scott Keepfer, Greenville News: Pitt

  • Todd Shanesy, Greenville News: Pitt

Week 4 prediction results

Total: 65-12 = 84%

  • Sammy Batten, Fayetteville Observer: 10-1

  • Carter Karels, Tallahassee Democrat: 9-2

  • Alexis Cubit, Louisville Courier Journal: 9-2

  • Jim Rice, Greenville News: 10-1

  • David Thompson, Fayetteville Observer: 9-2

  • Scott Keepfer, Greenville News: 9-2

  • Todd Shanesy, Greenville News: 9-2

Season results

Total: 253-76 = 77%

  • Sammy Batten, Fayetteville Observer: 38-9

  • Carter Karels, Tallahassee Democrat: 36-11

  • Alexis Cubit, Louisville Courier Journal: 34-13

  • Jim Rice, Greenville News: 38-9

  • David Thompson, Fayetteville Observer: 36-11

  • Scott Keepfer, Greenville News: 35-12

  • Todd Shanesy, Greenville News: 36-11

This article originally appeared on The Fayetteville Observer: ACC football predictions Week 5: College GameDay, Clemson-NC State