Christina Applegate ‘blacked out’ at Emmys 2024 appearance: ‘I live kind of in hell’ with MS

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She was the apple of their eye.

Christina Applegate got candid about living with multiple sclerosis and her rare appearance at the Emmys this year in a teaser clip for an upcoming interview on “Good Morning America.”

“I live kind of in hell. I’m not out a lot, so this is a little difficult, just for my system,” Applegate, 52, told “GMA” host Robin Roberts, 63, regarding her continued battle.

“But of course, the support is wonderful and I’m really grateful.”

Christina Applegate joked that she “blacked out” during her Emmys appearance in January and got candid about her multiple sclerosis diagnosis during a teaser clip for an upcoming interview on “Good Morning America.” GMA/ABC
Christina Applegate joked that she “blacked out” during her Emmys appearance in January and got candid about her multiple sclerosis diagnosis during a teaser clip for an upcoming interview on “Good Morning America.” GMA/ABC

The “Married … With Children” star, who was joined in the interview by Jamie-Lynn Sigler, also poked fun at her appearance on the January awards show.

“Were you able to take in the standing ovation?” Roberts asked.

“Actually I kind of blacked out,” Applegate replied. “People said, ‘Oh, you were so funny,’ and I’m like, ‘I don’t even know what I said. I don’t know what I was doing.'”

“I got so freaked out that I didn’t even know what was happening anymore,” she continued. “And I felt really beloved, and it was a beautiful thing.”

She quipped: “I probably shouldn’t say this, that audience stood up for everybody.”

Stunning in a red dress, and cane, the “Sweetest Thing” star appeared overwhelmed at the incredibly warm reception she received, and jokingly bashed the audience for mocking her. Kevin Winter/Getty Images
Stunning in a red dress, and cane, the “Sweetest Thing” star appeared overwhelmed at the incredibly warm reception she received, and jokingly bashed the audience for mocking her. Kevin Winter/Getty Images
Applegate told Robin Roberts of her Emmys appearance, “People said, ‘Oh, you were so funny,’ and I’m like, I don’t even know what I said. I don’t know what I was doing.” GMA/ABC
Applegate told Robin Roberts of her Emmys appearance, “People said, ‘Oh, you were so funny,’ and I’m like, I don’t even know what I said. I don’t know what I was doing.” GMA/ABC

Applegate’s candid interview with Roberts is set to air Tuesday.

Sigler, 42, who was diagnosed with MS when she was 20, and Applegate are slated to launch their brand-new podcast “MeSsy” on March 19, and will detail their experiences with the autoimmune disorder.

Applegate, meanwhile, revealed her MS diagnosis in 2021. She appeared overwhelmed when she presented the award for Outstanding Supporting Actress in a Comedy Series to Ayo Edebiri for “The Bear” at the time.

“You’re totally shaming me with disabilities by standing up,” she quipped, prompting several people to laugh. “It’s fine.” Monica Schipper/WireImage
“You’re totally shaming me with disabilities by standing up,” she quipped, prompting several people to laugh. “It’s fine.” Monica Schipper/WireImage
The Primetime Emmy Award Winner, who revealed her MS diagnosis in 2021, got an extended standing ovation after she appeared at the ceremony to present the award for Outstanding Supporting Actress in a Comedy Series to Ayo Edebiri for “The Bear.” Rob Latour/Shutterstock
The Primetime Emmy Award Winner, who revealed her MS diagnosis in 2021, got an extended standing ovation after she appeared at the ceremony to present the award for Outstanding Supporting Actress in a Comedy Series to Ayo Edebiri for “The Bear.” Rob Latour/Shutterstock

“Oh my God, thank you so much,” Applegate said while leaning on the arm of the show’s host, Anthony Anderson.

“You’re totally shaming me with disabilities by standing up. It’s fine,” she went on with a laugh. “Body not by Ozempic.”

The “Married … With Children” star, who was joined by longtime MS battler Jamie-Lynn Sigler, also poked fun at her appearance on the January award show. GMA/ABC
The “Married … With Children” star, who was joined by longtime MS battler Jamie-Lynn Sigler, also poked fun at her appearance on the January award show. GMA/ABC

Appelgate’s retreat from the public eye came after she hinted at retiring in February 2023.

“It’s my last awards show as an actor probably, so it’s kind of a big deal,” she told the Los Angeles Times in a profile prior to the SAG Awards that month.

“Right now, I couldn’t imagine getting up at 5 a.m. and spending 12 to 14 hours on a set; I don’t have that in me at this moment,” she continued.

Applegate was filming the third and final season of her Netflix comedy “Dead to Me” when she was diagnosed with MS.

“Jen Harding is the one who — who knows — quite possibly, the last one I’ll play,” she told Variety in 2022 regarding her character. “With my disease, I don’t know how capable I am. But this was a gift. This was a gift to me.”