The 48-year-old Bravo star is exiting the series ahead of its upcoming 12th season and is thanking her fans for "sticking with me through everything."
Frankel confirmed the news in a statement to ET, saying, "I have decided to leave the Housewives franchise to explore my next chapter. It's time to move on and focus on my daughter, my philanthropy and my production partnership with Mark Burnett, producing and starring in shows which represent a shift in the conversation for women. With the changes in modern culture, I want to highlight the strength, confidence, and unstoppable power that women have. My experience at Bravo has been an incredibly magical ride. I am so grateful to them for highlighting my entrepreneurialism and allowing me to pave the way for many women to achieve their goals. I am excited for my future. The best is yet to come."
This comes after Frankel shared the news with her fans on social media.
"I wanted to take a moment to write a personal note to you. I am so grateful to you for sticking with me through everything. You started this journey with me in my tiny apartment in my late 30s, wondering what would happen to me. I was broke, single, had no family and no idea what the future held," Frankel wrote on her Instagram on Wednesday. "I had big dreams and I never stopped, but I honestly didn’t know if I would ever get here. You helped me to get there."
"I would read your letters and messages and grow from your struggles. You would give me your honest opinion about my products and projects and helpful advice about divorce, relationships, motherhood, miscarriages, health, and surviving the death of a loved one and almost my own. You have shared your ideas with me and I have been inspired by and learned from you," she continued. "I am fortunate to have created a business and career that some people only dream of. I had a beautiful baby girl who is now 9 years old, and she has changed me as a human being. I was able to give back and help people all over the world who have been hit with the worst of unforeseen circumstances, which we will all continue together."
Frankel added that whatever goals one has, "GO for it. Whatever it is. Reach for your dreams in life and love and make the impossible happen, because it can happen and it WILL happen. Come from a place of yes and it’s yours for the taking."
"Thank you so much for your love and support. And stay tuned, you haven’t seen the last of me. There are many amazing things to come. I love you all and am so lucky to have you in my life! PS: New York City is still my playground," she concluded. ET has reached out to Bravo for comment.
Frankel has been a part of RHONY since 2008, leaving in 2010 before rejoining in 2015. Much of the TV personality's life was featured on the Bravo show, including the death of her on-and-off boyfriend, Dennis Shields. In the season 11 premiere of RHONY in March, Frankel recalled how she discovered that Shields had died.
"Dennis passed away three weeks ago in his apartment," Frankel recounted. "Tyler, his daughter, called me, hysterically crying and she said, 'My dad died this morning.' And I started screaming into the phone."
In the episode, Frankel also shared with her daughter, Bryn Hoppy, her final text message to her late boyfriend: "I love you, Dennis, and I always will. You're the most loving, beautiful man in the whole world and I'm sorry you were in so much pain. Now, you can really sleep."
For more on Frankel, watch below.