Baby Boy on the Way for David Arquette

David Arquette/Instagram

David Arquette has something exciting to Scream about: a new baby on the way!

On Wednesday, the actor took to Instagram to share a video of his 2-year-old son Charlie West holding an ultrasound photo to announce he and wife Christina are expecting their second child together.

“So incredibly blessed and honored that my wife @christinaarquette is pregnant with a baby boy!” the former In Case of Emergency star captioned the clip.

“Thank you Christina and humbled gratitude to G-D for this tremendous gift!” adds Arquette, 45. “Charlie and Coco are so excited and I am over the moon!!!”

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“Say, ‘Hi, brother!’ ” Christina says from behind the camera in the video, which shows Charlie kissing and snuggling the ultrasound photo.

“Baby?” he says.

“Yeah, it’s a baby in my belly,” his mom replies.

“Hi, baby!” he says before following up with, “Hi, brother!” and planting a sweet smooch on the photo.

View this post on Instagram

The best thing in life #love #family

A post shared by David Arquette (@davidarquette) on Oct 1, 2016 at 8:29am PDT

Aside from Charlie, Arquette is also dad to 12-year-old daughter Coco from his previous marriage to Courteney Cox.

And it’s likely the actor is ready to have a newborn around again.

“Since Charlie has come into my life, I love Coco more than ever,” he told PEOPLE in 2014 when his son was an infant. “Having a son has brought back memories and made me realize how much I miss enjoying her as a baby.”

The baby news comes a month after Arquette’s sister Alexis Arquette passed away from complications related to AIDS.

Jen Juneau