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Jane Kaczmarek
Jane Kaczmarek may be best known for being mom to a gaggle of rambunctious boys in the sitcom "Malcolm in the Middle," but in real life she didn't become a parent until the age of 41, when she gave birth to daughter Frances in 1997. She and now-ex-husband Bradley Whitford went on to have two more children, George, born when Kaczmarek was 44, and Mary, who the actress gave birth to at age 46.

What to Read Next

First-Time Moms After 40

March 27, 2012

Halle Berry, Salma Hayek, and Mariah Carey are just a few of the celeb moms who entered motherhood after they turned the big 4-0. -- By Kathleen Perricone and Lizbeth Scordo, omg!